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#Efficacy
Natalie E. Dean, PhD
nataliexdean
Warning - some in-the-weeds tweets about vaccine efficacy trials, new strains, and decision making under uncertainty. I offer more questions than answers, but hopefully it can generate some discussion...1/6 For
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PoliMath
politicalmath
The CCP's goal is 100% about saving face and bolstering nationalismThey do this by1) developing their own vaccine2) reporting inflated numbers so they look good by international comparison3) trusting western
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Yoong
yoongkhean
Some info on vaccine efficacy. We tend to make the mistake of 95% efficacy (Pfizer) being 95 out of 100 is protected from the disease while 5 out of 100
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Natalie E. Dean, PhD
nataliexdean
A few tweets on a topic that keeps coming up in discussion. There are many different types of vaccine efficacy - efficacy against infection, against transmission, against disease, and against
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Dr. Theresa Chapple
Theresa_Chapple
To hear public health professionals with large platforms call the vaccine 95% effective, instead of distinguishing between efficacy and effectiveness, really concerns me. Vaccine efficacy is how well the vaccine
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Hilda Bastian, PhD
hildabast
Confirmation on the 78% for mild Covid-19 subgroup for Sinovac's inactivated vaccine CoronaVac: excluded people who didn't need medical care. Overall efficacy likely in the low 60s https://archive.vn/Ms4nM Depending on
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Maxibon
thiscassgirl
Initial reporting was lower efficacy sure but ongoing trials showed higher. We aren't getting the pfizer one in large doses as other govts had dibs based on investment & the
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Yuliya Shneyderman
Yuliya
A note on vaccines. The numbers we are seeing from Moderna and Pfizer are efficacy, not effectiveness. Efficacy is a number calculated during clinical trials - these are highly controlled
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Florian Krammer
florian_krammer
1) The low efficacy of the Novavax vaccine candidate against the B.1.351 is concerning. However, the data is also reassuring in many ways. First, the vaccine itself worked very well
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Pfizer Inc.
pfizer
BREAKING: We are proud to announce, along with @BioNTech_Group, that the Phase 3 study of our #COVID19 vaccine candidate has met all primary efficacy endpoints. The study reached 170 confirmed
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Yoong
yoongkhean
We shouldn’t be too fixated on vaccine efficacy. What ultimately is important (& I suspect most of us are talking about) is vaccine effectiveness (VE).Vaccine efficacy is % of reduction
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Derek Gatherer
DerekGatherer
What does a #COVID19 #vaccine with 90% #efficacy imply? It means that 90% of people who are vaccinated will develop sufficient immune response to repel the virus without symptoms (they
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Ed MD
notdred
A thread on vaccine efficacy and why you should get whichever vaccine you're able to access, without stressing about "70% efficacy" or "95% efficacy". 1/10 "Vaccine efficacy" in these phase
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F. Perry Wilson, MD MSCE
fperrywilson
Ok the @moderna_tx vaccine data is up at the @fda in advance of the #vrbpac meeting 12/17. Let's take a look! THREAD Starting with the big news - the cumulative
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Natalie E. Dean, PhD
nataliexdean
VACCINE EFFICACY 101: A biostatistician's primerTen tweets to cover:- How is vaccine efficacy calculated?- Distinguishing between infection, disease, & severe disease.- Measuring reduced infectiousness.- Vaccine efficacy vs. effecti
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Rajeev Venkayya MD
rvenkayya
Agree with this piece and the "strawman" messaging at the end. One clear opportunity is to focus on prevention of severe disease and death (where most vaccines are very efficacious)
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