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#Efficacy
Eric Feigl-Ding
DrEricDing
NEW—official full trial results of Pfizer/BioNTech vaccine in 43,448 people:95% efficacy w/ 2 doses52% efficacy after 1st dose (before 2nd)10 severe cases, 9 were in placeboSerious adverse events low &
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Prof Francois Balloux
BallouxFrancois
The recent Novavax vaccine trial reported lower efficacy in its SA arm. This is plausibly caused, at least in part, by the high frequency of the B 1.351 lineage in
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Robert Peston
Peston
If the UK government came late to the Moderna party, and has bought less of its vaccine than is ideal, the fault is not that of Kate Bingham and her
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🕷️The wife scientific🕷️
ProfKatieEwer
Our new preprint on the efficacy of a single dose of the Oxford/AZ ChAdOx1 nCoV-19 #vaccine-76% efficacy against symptomatic infection from day 22 to day 90 post vaccination in 17,177
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Theo Sanderson
theosanderson
1/ Had another look at the new Maccabi data. (tl;dr: things look good, but nothing beats a randomised trial) https://theo.io/post/2021-01-31-maccabi-2/ 2/ I extracted the data from the "MHS" Kaplan-Meier plot
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Meg Tirrell
megtirrell
Novavax gives us first vaccine efficacy data we’ve seen against B117 (UK) and B1351 (South Africa) variants, from trial results just reported.In UK the news is good: 89% efficacy in
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Alan U. Kennington
kennington_u
Vaccine "critical herd immunity strength".Let's call it CHIS for now. Assume 100% coverage.Effectiveness E gives CHI if R ≤ 1/(1−E) = CHIS.So E=70% gives CHI if R ≤ 3.33.So CHIS
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Dr Zoë Hyde
DrZoeHyde
(1/7) Spectacular news from Novavax. The efficacy of their vaccine matches Pfizer & Moderna, but it doesn't have the same ultra-cold storage requirements. UK phase 3 trial results:95.6% original COVID-1985.6%
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Rajeev Venkayya MD
rvenkayya
This is very good news indeed, and the *potential* implications go well beyond the @pfizer #COVID19 vaccine. While we just have the press release, it's worth reviewing what this *could*
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Abir Ballan 😊
abirballan
@JuliaHB1 please ask @carlheneghan 1) Has the asymptomatic spread theory upon which lockdowns were justified been supported? 2) What were the results of the vaccine animal trials?3) What are the
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Hilda Bastian, PhD
hildabast
Well, dear readers, my take on "the winning formula" for Oxford/AstraZeneca did not age well. According to the Indian manufacturing partner, it isn't the "low"-dose-1st subgroup. It's another subgroup, perhaps
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Muge Cevik
mugecevik
There is a lot of confusion about the efficacy of AstraZeneca/ChAdOx1 vaccine against COVID19 due to B.1.351 / 501Y.V2 - summarising the results of phase 1b/2a double-blind randomized trial conducted
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Eric
IAmTheActualET
Anders Tegnell 10/28: "Experiences in Europe are not that great…countries with huge increase in cases have a legal obligation to wear face masks…it's quite clear masks are not going to
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Dr Emily Grossman
DrEmilyGrossman
Concerned re the new vaccine strategies? Worried that delaying the second dose is a bad idea or that it might make the virus resistant? Confused re mix and match vaccines?
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𝔻𝕣𝕃𝕪𝕟𝕟𝔽𝕪𝕟𝕟 🇺🇸 👩🏽⚕️🧬💊🥼🩺🦠🌿
LynnFynn3
1) Thread addendum to my previous vaccine study analysis- Looking at "final" Pf*zer, pre-EUA data...Looks like they dropped the efficacy population from 44,000 to 36,000...and there's this little gem "Some
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Jamie Triccas
TricckyLab
Really interesting data coming out of latest report on Oxford/AZ vaccine efficacy trials (another one!).A little on this.#COVID19 #CovidVaccine https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3779160 What did they find?Trial looked at p
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