Agree with this piece and the "strawman" messaging at the end. One clear opportunity is to focus on prevention of severe disease and death (where most vaccines are very efficacious) rather than overall efficacy. How'd we end up here? 1/ https://twitter.com/DLeonhardt/status/1351211925816946695

In the Ph3 clinical trials, the fastest way to assess efficacy is to count *all* cases, including mild disease. Vaccine protection against severe disease is usually better than mild disease, and that's what we're seeing in the trials. 2/

The problem is that the "overall efficacy" has become the main talking point, obscuring the fact that so far most vaccines appear very good at preventing the worst outcomes of COVID, which is important to everyone. That needs more emphasis. 3/

And yes we need to improve the messaging on transmission, explaining that we expect benefit based on experience and the efficacy seen so far. But we also need to be upfront about what we don't know and how individuals can manage that risk as we learn more. 4/

Reupping this great thread on the topic from @notdred. 5/ https://twitter.com/notdred/status/1349740142454517760?s=20