#Placebo

Peter Suzman

Biomaven

Second thread on $FGEN roxadustat in NDD.First thread here:https://twitter.com/Biomaven/status/1304433750911188993?s=20 So $FGEN stock price was basically unchanged w/ $AKBA's failure, even though this likely removed a significant poten

Jonathan Engler 😀

jengleruk

Genuine question:At https://www.fda.gov/media/144245/download it can be seen that in relation to the Pfizer vaccine:The 95% effectiveness is based on:162 cases / 22k receiving placebo with mild symptomatic Covidvs8 cases /

More Than A 💊 Counter 🇬🇭

GhanaboyPharmd

**Thread**The FDA has just recently granted an EUA to Lilly's Antibody treatment Bamlanivimab for COVID19This particular study is an ongoing phase 2 trial that involved outpatients with recently diagnosed mild

Peter Suzman

Biomaven

Because it is all very confusing, let me once again set out my perspective on analyzing AEs in a trial (like the $FGEN roxadustat NDD trial) where there are many

Robin Monotti

robinmonotti

"The revised Pfizer [trials] numbers could also be reported as 99.9% of people in the vaccine group and 99.1% of people in the placebo group didn’t test positive. [never had

A Marm Kilpatrick

DiseaseEcology

FDA Pfizer/BioNTech vaccine efficacy results are great, but aren't nearly as great as presented for severe infections.Everyone has seen fig below on cases in vaccine (blue) & placebo (red) over

Zucker Doctor

DoctorLFC

The Bharat Biotech (Covaxin) vaccine he received on November 20 has a two dose schedule at a 28-day interval. He only received the first dose. Phase 3 trials (28k people)

Eric Meyerowitz, MD

EricMeyerowitz

1/ Key question right now is how much SARS-CoV-2 vaccines will decrease transmission.Data from Regeneron mAb cocktail prevention press release may help us think about thishttps://investor.regeneron.com/news-releases/news-release-details/reg

Reuters

Reuters

The subject line on the email received by @Reuters reporter @stecklow last week said simply, 'Test'. It contained the results of a private blood test he had undergone the day

VOICE CARE CENTRE

voicecarecentre

I want to redefine PLACEBO. “Placebo” is considered a dirty word, a trick, a word reserved to describe saline injections and sugar pills. Somehow, ‘placebo’ has become synonymous with quack

David

PrimaryCarePAC

Have you read Gualano 2010:“Creatine supplementation does not impair kidney function in type 2 diabetic patients: a randomized, double-blind, placebo-controlled, clinical trial.” Why consider #creatine and diabetes?Creatine has shown be

C-19 & Vitamin D

c19d3k2

n=240, 2-center "double-blind, randomized, placebo-controlled trial [...] in Sao Paulo, Brazil" of 1-time 200k IU D3 vs. placebo did not see a difference in timespan from randomization to discharge or

Jason Gallagher

JGPharmD

Couple of notes on the Moderna VRBPAC FDA briefing document. A thread 1/ #VRBPAC #COVID19Vaccinehttps://www.fda.gov/media/144434/download This is just beautiful. Note that the 2nd dose was given at day 28, and

F. Perry Wilson, MD MSCE

fperrywilson

Looking through the @pfizer data submitted to #vrbpac now. Fascinating stuff here. Thread. 1/ Baseline characteristics. Not bad. ~10% Black. Would have liked to see more >=75 years old. 2/

Yoong

yoongkhean

Some info on vaccine efficacy. We tend to make the mistake of 95% efficacy (Pfizer) being 95 out of 100 is protected from the disease while 5 out of 100

Dr Bryan McElroy

BryanMcElroy8

1/ I gave a talk to a group of GPs yesterday evening re:- the history&evolution of DSM (most did not have any awareness of the origins of diagnoses) - The

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