#Placebo

Andy Grieve

AndrewPGrieve

https://twitter.com/T_Allen1998/status/1323335976991756290?s=20@statsepi Part of the problem is using the same symbols for different things. In a superiority trial delta is the minimum clinical difference, or as @stephensenn calls it "

Katy Stephenson, MD, MPH

k_stephensonMD

Hi friends! Today's news about the NIH-Moderna #COVID19 #vaccine is astonishingly good. I've never seen my colleagues - weathered, skeptical professor types - so giddy and delighted and surprised. Here's

Sizwe sikaMusi

SizweLo

What’s the difference between vaccine efficacy and effectiveness, and what do vaccine makers mean when they say their therapies are “95% effective”?[Thread] Vaccine efficacy refers to the percentage change in

Jean Marc Benoit MD

JeanmarcBenoit

Takotsubo cardiomyopathy. Numerous case reports of this condition in association with covid. Theory is that surge of stress hormones (catecholamines such as adrenaline and noradrenaline) brought on by emotional shock

Zack Davisson

ZackDavisson

So, vaccines. I worked for an IRB, meaning Independent Review Board. This is a third-party entity that oversees clinical testing of new drugs. No testing can be done without IRB

Libbie Hawker

LibHawker

I'm doing a lot of really fascinating research into ethnobotany of the Plains tribes (especially Ponca) for part of the novel I'm working on now. What incredible information! My character

Carl T. Bergstrom

CT_Bergstrom

No cross-strain protective immunity? Based on what evidence? Even the linked story—which @UW_IHME wrote—says nothing of the kind.I think people still listen to @UW_IHME even after last spring's modeling fiasco.

D

ez_dee

It just occurred to me.The vaccine is not the end goal here, not this one anyway.The goal is compliance. If they roll out this vax & it has no harmful

Tim Norfolk

norfolk_tim

1/10How should we manage pts with a below knee DVT?A short tweetorial trying to address this commonly encountered conundrum... 2/10You see a fit and well 48 F with painful swelling

BatFlu

ItsABadFlu

Whether you like it or not, after today's announcement, there's a good possibility the vaccine is the only way the restrictions/lockdowns end, on the caveat it is voluntary.A short thread

Giorgio Gilestro

giorgiogilestro

Living in the UK, I've heard lots of triumphalistic announcements regarding AZ approval on the radio so I think it's wise to offer a complete perspective of what happened. Here's

Tony Breu

tony_breu

1/Does the tryptophan in turkey really cause a food coma?I've heard this repeatedly, while also being told that it is a myth. Let's have a look at the physiology of

Deirdre Tobias, ScD

deirdre_tobias

The DPP: $Huge NIH-funded trial (N=3200) in the 1990s. Conclusion: randomized diet/lifestyle significantly reduced T2D more than metformin or placebo. Big 58% reduction. The diet? Reduce total fat as much

Eric Feigl-Ding

DrEricDing

Worrisome discovery—Among placebo group for Novavax’s vaccine in South Africa: people with prior #COVID19 infections appeared just as likely to get sick as people without prior infections—means past infection wasn’t

Dr. Ali Nouri

AliNouriPhD

1. The #Moderna vaccine, just like Pfizer/BioNTech, is a messenger RNA vaccine. #SARSCoV2 is covered w/Spike proteins that it grabs human cells with. The vaccine consists of small genetic material

Jason Pogue

jpogue1

I promise that if #hydroxychloroquine was an effective therapy for #covid19 we would tell you. Many of us (myself definitely included) were hopeful that it would be at the onset

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