#Variants

Joshua Gans

joshgans

Time for a threat on the J&J vaccine whose efficacy results were released today. https://www.nytimes.com/2021/01/29/health/covid-vaccine-johnson-and-johnson-variants.html?action=click&module=Spotlight&pgtype=Homepage [1/n] First

Amir Attaran

profamirattaran

Three comments:1. If the AZ vaccine can’t stop mild and moderate illness in the South African variant, that’s likely true for the other vaccines too.2. What matters most is stopping

Katalin Susztak

KSusztak

Kidney disease genetic risk variants alter lysosomal beta-mannosidase (MANBA) expression and disease severity https://stm.sciencemag.org/content/13/576/eaaz1458 The study is lead by @Xiangchen_Gu @XinSheng7 and Holly Yang. Kidney function G

Bunsen and Beaker

bunsenbernerbmd

Have you heard about the “variants” of #COVID19 ?Let’s break it down!!!Yep- there are always variants of viruses out there. When they copy themselves they make mistakes and POW you

Ashleigh Tuite

AshTuite

Here’s the thing that continues to baffle me with our `wait and see’ approach to more transmissible VOCs in Ontario. All of the things we need to do are things

Jeremy Farrar

JeremyFarrar

Finland detects UK & SA variants. As immune pressure on virus grows, evolution will speed up & any variants that escape that immunity will have selective advantage. Both variants huge

Dr. Angela Rasmussen

angie_rasmussen

With global spread, national border closures seem like a pretty facile solution to hypothetical more infectious variants that haven’t emerged yet or been imported. Int’l travel isn’t a selection pressure

Matthew Thompson

mattuthompson

The UK is taking action against new variants. Closing borders. Surging testing. And yet the impression from last night’s presser was that the South African variant wasn’t the most pressing

Greg Butterfield

redguard1971

So on any random day you can visit @nytimes @washingtonpost @CNN etc. and see several things side by side (a thread): 1- Schools should be reopened immediately, even without

Catherine Finnecy

cfinnecy

"No single intervention, other than a complete, pre-emptive closure of borders, or the mandatory quarantine of all visitors upon arrival in designated facilities irrespective of testing history can fully prevent

Dr Sumaiya Shaikh

Neurophysik

In the light of various new homologous strains, in addition to the UK one, emerging globally, that may be evolved to escape the neutralising antibodies post vaccinations. It is in

Ryan McNamara 🧬

Ryan_Mac_Phd

Viruses change over time, particularly when acclimating to a new host. Variants increase as prevalence increases. The Great Barrington Clowns proposed letting the virus run rampant through young adults as

Amir Attaran

profamirattaran

Viral strains in the UK. See the orange bit which picks up in December and rapidly crowds out the competition?That strain is just getting going in Canada.We are going to

Mac n’ Chise 🧬🧫🦠

sailorrooscout

Concerning the SARS-CoV-2 variants that were first identified in the UK (B.1.1.7), South Africa (B.1.351), and Brazil (P.1), their specific mutations focus on altering the fitness of the virus by

Monica Gandhi MD, MPH

MonicaGandhi9

Know very tempting to feel nervous about variants. Please don't: 1) RNA viruses do mutate and those more fit spread more readily; 2) SARS-CoV-2 has much lower mutational rate than

Sentiv

sentivcapital

$FSDC (thread): Merger with Gemini in January. Focused on huge GA/dAMD market (think multiples of wAMD). No current Tx, $APLS C3 first to market, with other C inhibitors to follow

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