#Germline

Samuel Marsh, Ph.D.

samuel_marsh

New year seems like as good a time as any for another reminder: Be careful with your animal models! This edition brought to you by the Cre/Lox system. #methodsmatter 1/n

Saud AlDubayan, M.D. د.سعود الدبيان

s_aldubayan

Very excited to see our work on deep learning germline variant characterization out today in @JAMA_currentHere is a quick thread on the major findings and takeaways from this study. #CancerResearch

Veera M. Rajagopal

doctorveera

This is an ingenious paper. No doubt about that. But it is getting media attention for the wrong reasons. 1/8https://www.nature.com/articles/s41588-020-00755-1 This paper is one of 100s of papers from deCODE

James Walker

James_Walker303

A thread on our exciting discovery of niRNAs that determines plant paternal epigenetic inheritance and the comprehensive mechanism via their trans activity at both locus and cellular levels! https://www.biorxiv.org/content/10.1101/2021.01.2

Dr. Coleen Murphy, flaunting my PhD

ctmurphy1

As promised, a thread explaining our newest BioRxiv paper, where we’ve discovered that C. elegans can transfer memories of pathogen avoidance to naïve individuals.https://www.biorxiv.org/content/10.1101/2020.12.28.424563v1 What if one wo

Alice Wong

SFdirewolf

Disabled people told ya “A powerful gene-editing tool called Crispr-Cas9...can cause serious side effects in the cells of human embryos, prompting them to discard large chunks of their genetic material,

Arjuna Rajakumar

ArjunaRajakumar

New preprint up on bioRvix! We compiled a full #ontological series of #development for #Monomorium pharaonis - for all castes! Co-first authored with the amazing Luigi Pontieri and a great

Luiza Moore

luiza_moore

After many years and a real journey, we are excited to share our preprint on mutations in human cells!We studied multiple samples from the same individuals to explore mutational landscapes

Nick Burton

BurtonNick

It’s been a big two weeks in the field of multigenerational effects in C. elegans with four different papers published or up on bioRxiv in a two-week window! Still reading

Tim Coorens

TimCoorens

Our latest paper is out today in NEJM! Together with Sam Behjati, I explored the origins of bilateral neuroblastoma from somatic mutations. [1/6]https://www.nejm.org/doi/full/10.1056/NEJMoa2000962 Neuroblastoma is a common childhood cancer

Eli Van Allen

VanAllenLab

Spent some time over the holiday thinking about the convergence between the two areas of my professional life - cancer research & clinical oncology - and areas of innovation spanning

Inquisitor Papi Juan el Moreno

neogranandino

After much thought yesterday I've decided options and a conclusion of where possibly Jesus' SRY Gene must have come from. First, some considerations: 1) it's affirmed in a bunch of

Petr Svoboda

SvobodaLab

EPIGENETICS REPETITORIUM ... a thread DNMT1 operates on hemimethylated CpG dinucleotides present in newly replicated DNA and restores symmetrical CpG methylation. Heterochromatin emerges from a crosstalk between DNA methylation and

Zoé

ztsamudzi

I appreciate the thrust of this piece about how analogies about white supremacy/nationalism obscure the problem at hand, but it doesn't consider the issues of relying on disease pathology to

Amit Kulkarni

AmitKulkarniMD

#FDA recently approved #pembrolizumab- a tissue agnostic indication in metastatic tumors with high #TMB (>10 mut/MB) using Foundation One Dx companion diagnostic test. I want to share a tweetorial on

Alex Shoushtari, MD

alexshoushtari

Hi #medtwitter + new onc fellows! I treat patients with advanced #melanoma, especially rare ones like #uvealmelanoma (UM). This #tweetorial will discuss:1) Why UM is unique 2) When does(n’t) immunotherapy

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