“Administered to cells to repair a mutation that can cause hereditary blindness, the Crispr-Cas9 technology appeared to wreak genetic havoc in about half the specimens that the researchers examined, according to a study published in the journal Cell on Thursday.”
“The consequences of these errors can be quite serious in some cases, said Dieter Egli, a geneticist at Columbia University... Some cells were so flummoxed by the alterations that they simply gave up on trying to fix them, jettisoning entire chromosomes...”
"Crispr-Cas9 treatments have already been given directly to people to treat conditions like blindness — a potential cure that affects that patient, and that patient only."
"But modifications made to sperm, eggs and embryos can be passed to future generations, raising the stakes for any mistakes made along the way."
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