#Colchicine

Martin Landray

MartinLandray

Colchicine for non-hospitalised pts with COVID-19Stopped by investigators “due to logistical issues related to maintaining the central study call center...& ...perceived need to disseminate the study results rapidly”Travesty.https:/

Ashwin Varma

varma_ashwin97

I can scarcely believe this, but if so, this is an amazing result. @matthewherper @GermHunterMD @walidgellad @mikejohansenmd https://thecanadian.news/2021/01/23/major-breakthrough-large-study-shows-effectiveness-of-colchicine-to-treat-covid

Nick Mark MD

nickmmark

Long awaiting #COLCORONA RCT now in #PrePrint:-4488 non-hospitalized pts with suspected #COVID19 randomized to #colchicine (0.5 mg BID x3)vs placebo-1° outcome (composite death/hospitalization) was NOT significant-interesting findings in s

John Mandrola, MD

drjohnm

Analysis of #Colcorona Trial results in #COVID19 outpatients with risk factors.I will add Bayesian take and focus on the ITT. (cite @ProfHayward here) Primary endpoint death or Hospitalization -- legitLink

Holly Witteman, PhD

hwitteman

The #colcorona preprint was posted last week. I was busy in a review panel so this is coming a bit later, but here’s my take, as a scientist who has

Charlotte Sharp

sharpcharlotte

Some crystals of learning on gout from Ed Roddy @Keele_PCSC (get it?! )Indomethacin no more efficacious than other NSAIDS, worse SEsThink of gout as a chronic disease of monosodium urate

Peter Horby

PeterHorby

The RECOVERY Data Monitoring Committee reviewed data on patients randomised to convalescent plasma vs. usual care. The preliminary analysis based on 10,406 randomised patients with 1873 reported deaths shows no

RiderToast, functional overlay syndrome haver

RiderToast

In the pilot of House the patient has a seizure in the cold open. Her neurocysticercosis would have been found on MRI seizure protocol in the ED. End of episode.

Joanna Poole 💙

Jopo_dr

More biochimestry series: true to textbooks, everything involved in a biochemical pathway, tends to have a series of reduction (proton donation) or oxidation reactions. Although end products often just seem

pik mukherji

ercowboy

Ok, I am sorry we are here, but here we are.Many of you health care workers are where I was a few months ago.Listen: Testing will be quickly overwhelmed or

Dr. Urso

richardursomd

How does it makes sense that the CDC, the FDA and the NIH which saw exactly zero patients for the year, are saying not to treat covid prior to hospitalization.

Martin Landray

MartinLandray

RECOVERY Update:30,000 patients now enrolled in one country in 10 months.The most extraordinary effort.And still ongoing. In the words of the independent Data Monitoring Committee:"Thank you for your continuing help

Joanna Poole 💙

Jopo_dr

This is such an elegant paper (I love ATS papers!) about pathophysiology of severe Covid; it's the host response we are treating, not the virus... Areas of inflammation are highly

Nikolas Dietis ᴾʰᴰ

Dietis_Lab_UCY

Παίρνω αρκετά emails και μηνύματα με ερωτήσεις για την κολχικίνη. Αξίζει ο "ντόρος" που γίνεται; Υπάρχει χώρος για αισιοδοξία; Θα

Adinda Wafdani Putri, dr.

_sotoyisme

Gotta share this to my twitter world:For this pandemic, there’s a greater chance of survival for those getting infected 3 months later like June 2020 than those who got infected

Kurt "Masks Save Lives" Eichenwald

kurteichenwald

This is an important thread. It is from someone who treats COVID patients who wants to get info out on what is happening. I will give one point up top:

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