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Joanna Poole 💙
Jopo_dr
It sounds a bit homeopathic but the more I read into metabolism and inflammation and circadian physiology the more I seriously worry about feeding our patients continuously and overnight a)
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So I am making a thread on serotonin trials in covid because keeps coming up courtesy of @farid__jalali and the fact that about 70years of respiratory physiology recognise it as
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This is such an elegant paper (I love ATS papers!) about pathophysiology of severe Covid; it's the host response we are treating, not the virus... Areas of inflammation are highly
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Have been trying to find ways to describe to myself why pandemic is emotionally harder (you see people asking why doctors/nurses aren't used to death) it's cos firefighters wouldn't want
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Whenever I can't understand something in medicine I tend to go back to primitive physiology because the diversity we have and the biochemistry we have has been decided by what
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Oh medtwitter I have found one of my coolest evolutionary facts ever! I was looking at evolution of innate immune system. It's very old, below vertebrates. We didn't get adaptive
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Medicine in 2050:Patients lie suspended above their own beds with anti gravity devices to avoid pressure damage but some gravity devices to prevent bone and muscle loss, developed from space
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Little history of Lung Protective Ventilation [LPV] Ventilation first became widespread in the polio pandemics of the 20th century. Prior to that it has consisted more of using bellows to
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I know some people are really struggling and maybe some people even pathologically struggling. I know what it feels like to be shaking crossing the hospital threshold, goosebumps, and visceral
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Essential reading for intensivists: things you didn't even dream were going on in your ventilated patients' lungs. With credit to @robertpdickson who does some very clever translational work on lungs
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More biochimestry series: true to textbooks, everything involved in a biochemical pathway, tends to have a series of reduction (proton donation) or oxidation reactions. Although end products often just seem
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Covid intensive care is: hourly arterial blood samples to check oxygen levels, lines placed into arteries to sample them, lines in the jugular vein to replace electrolytes we have driven
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