#Variants

Cathy Newman

cathynewman

Lots to digest from the man who led Oxford jab team Prof Sir John Bell: he tells me South African/Brazil #covid variants are a “big problem” bc “changes are pretty

Ryan McNamara 🧬

Ryan_Mac_Phd

Very interesting piece by the @nytimes in regards to SARS-CoV-2 surveillance, or lack thereof, in the U.S. Having been involved in sequencing SARS-CoV-2 among the population, I had a few

Prof. Devi Sridhar

devisridhar

3 phases:Winter: ensure NHS doesn’t collapse. Strong restrictions on mixing.Spring: Suppress to low levels & get robust mass testing & supported isolation in place.Summer: Eliminate & protect low prevalence with

Xihong Lin

XihongLin

The TOPMed flagship paper of 54K whole genome sequences finally appeared in @nature. Thanks for the hard work of many TOPMed colleagues. I am honored to work with many of

Hensley Lab

SCOTTeHENSLEY

There has been recent discussion of how this influenza virus mouse study that I completed as a postdoc potentially relates to current SARS-CoV-2 evolution, so I thought I would write

Kimberley Kendall

DrKKendall

This is a fantastic paperhttps://ja.ma/39krtFO Martin et al examined for 92,455 individuals:- exome sequencing data for 31 pathogenic, recurrent CNVs,- electronic health record data (EHR) 0.8% (n = 708) had

Biohospitalix

BioHospitalix

Le gouvernement vient de faire paraître un DGS urgent sur les variants Anglais / Sud Africains et Brésiliens.L'inquiétude n'est plus trop sur l'anglais mais sur les deux suivants.Comme je vous

Dr. Rob Davidson #WearAMask

DrRobDavidson

Here's a little pep talk for those experiencing Pandemic Fatigue. First off, this is a real thing & you shouldn't be ashamed. I’m hearing from patients, family & friends that you’ve

Goncalo Abecasis

gabecasis

This paper was a longtime coming. In no particular order, some of the interesting things to learn from the sequencing and analysis of 53,831 human genomes. 1/nhttps://www.nature.com/articles/s41586-021-03205-yPDF: https://www.nature.com/art

Aaron Derfel

Aaron_Derfel

1) On the same day authorities announced 86 probable cases of the more contagious #COVID19 variants in Quebec, Premier François Legault announced he will reopen movie theatres, public pools and

zeynep tufekci

zeynep

Interrupting your doomscrolling with more good news. As most had expected, the vaccines continue to work well against the new variants. Our problem remains producing enough of these amazing vaccines

Laurence Howe

laurencejmshowe

A short summary of a preprint on interpreting Mendelian randomization analyses with categorical exposures with @nm_davies @mendel_random and @tudballstats https://www.medrxiv.org/content/10.1101/2020.12.14.20248168v1 (1.) Categorical phenot

Deepti Gurdasani

dgurdasani1

Concerning data from PHE today suggesting that sequencing shows that there are 11 cases of the UK variant (B117) identified that also have the E484K mutation (the one found in

George Yarrow

george_yarrow

The new variant of the virus *is* becoming dominant in London & surrounding areas said Sir Patrick Vallance. *Has* become dominant would have been more appropriate (>60%): we now discover

Mustafa Hirji

mustafahirji

When the UK reopened from their fall lockdown (graph), cases were still high & variants were able to surge. The UK went back into lockdown within 3 weeks. Germany is

Jase Gehring

JaseGehring

Eric's generally pretty great, but this is clearly wrong and the wrong way to consider this problem. A more useful calculation would be number of 30kb genomes within, say, 5%

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