#Trials

covid19indiaorg

covid19indiaorg

The expert committee of CDSCO met on 30/12, 01/01 and 02/01 to deliberate on accelerated approval of vaccines. Recommendations made on each day have been officially published. In this thread,

Sam Sims

DrSamSims

RCTs tell us 'what works', right? They give us unbiased causal estimates, right?New paper with @jakeanders @mjinglis & Hugo Lortie-Forgues: https://bit.ly/32VdEvL It's increasingly recognised that RCTs are often underp

Governor JB Pritzker

GovPritzker

With the @US_FDA releasing its analysis of the Pfizer-BioNTech vaccine ahead of the December 10th meeting, today I want to directly address those of you who may be hesitant to

Natalie E. Dean, PhD

nataliexdean

As @hankgreen nicely points out, we have to be careful that "we don't know whether the vaccine reduces transmission" doesn't morph into "the vaccine doesn't reduce transmission." How do we

bodhidave

bodhidave3

1/13Quickly sketched thread on looking at how we look at things... 2/ Doing more reading on Socrates, I happened to look at two articles back-to-back today about his trial for

Thijs Bouwknegt

thijsbouwknegt

Next week the International Criminal Court renders its 1st verdict in its first “situation” (atrocity crimes by the Lord’s Resistance Army in #Uganda). It concerns the #ICC’s most complex defendant,

Christine Gibson MD

GibtrotterMD

Watched vaccine webinars Alberta Health Services and Public Health Agency of Canada, now sharing takeaway points. This vaccine is critical, lucky that the ones approved by Health Canada 95% effective.

Rajeev Venkayya MD

rvenkayya

THREADHow were the first #CovidVaccines developed in less than a year without cutting corners?The vast majority of vaccine development time is spent *preparing for* Phase 3: the final large-scale, costly,

The Lancet

TheLancet

NEW—First full results from interim analysis confirm that the Oxford #COVID19 vaccine is safe and efficacious against symptomatic COVID-19 disease: https://hubs.li/H0CcSs60 (1/6) The vaccine protects against symptomatic disease in 7

Sandhya Ramesh

sandygrains

Hi Saket, most things mentioned in this thread are normal and expected. There are many other reasons to question the vaccine approval process, but these have an explanation; documentation is

Ubaka Ogbogu

UbakaOgbogu

So let's talk about a Black person being the first vaccine recipient in the U.S. This is a massive personal sacrifice that will go a long way in encouraging more

Jherane

Jherane_

The way we centre white women and erase the power dynamics of slavery & race in the retellings of Salem Witch Trials... https://twitter.com/NaijaFlyingDr/status/1287331967378370565 The fear of African, Afro-Caribbean, and Native

Dr. Ali Nouri

AliNouriPhD

The science pledge by vaccine manufacturers falls short because it leaves open the possibility of a pre-election Emergency Use Authorization for a vaccine. That would be viewed as political and

Anupam Singh

anupampom

While Favipravir and Coronil Trial are being criticized for lack of Blinding and gaining approval via Press Release. Have major drug trials done better?1. RECOVERY. Open label(No blinding). Evidence dexamethasone

Shane Crotty

profshanecrotty

5/ I got a number of questions yesterday related to COVID-19 vaccines, vaccines in general, and the Pfizer clinical trial interim results, so I will answer several of the big

Rupert Pearse

rupert_pearse

Recent trial results show some promise for Tocilizumab in the treatment of severe COVID-19. Welcome news at a difficult time and excellent work from @remap_cap & @NIHRresearch. But the results

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