#Mutation

Eric Feigl-Ding

DrEricDing

BREAKING—new #B117 variant & vaccine data from research lab shows mutations in B117’s spike protein yields a ~3.8x reduction in efficacy of vaccine-generated neutralization antibodies compared to wildtype (WT)

Eric Feigl-Ding

DrEricDing

NOT GOOD—so it seems government researchers have discovered that the already more contagious #B117 has further acquired the other troublesome E484K mutation seen in #B1351 & #P1 variants—in 11

Monica Gandhi MD, MPH

MonicaGandhi9

One thing that struck me tonight is that the UK roll-out of vaccine is much more in line with public health and practicality than US rollout which is much more

Reuters

Reuters

A new variant of the pandemic SARS-CoV-2 coronavirus is spreading rapidly in Britain and prompting high levels of concern among its European neighbors. The strain is said to be up

Dr. Angela Rasmussen

angie_rasmussen

Viruses don’t evolve to get around masks, distancing, or disruption of the virus particle by detergents or disinfectants. Mutation doesn’t defy the laws of physics. B.1.1.7 is transmitted the same

elleven 🤜🏻🤛🏻

KIRlMSON

information/theory thread on kirishima’s teeth. when we see kirishima as a lil baby, his teeth are straight (ew) and normal. although there are the occasional slip ups with forgetting the

Bloom Lab

jbloom_lab

We mapped all #SARSCoV2 mutations escaping key antibodies used to treat #COVID19 (https://www.biorxiv.org/content/10.1101/2020.11.30.405472v1). Surprising observations: one amino-acid mutation escapes *both* antibodies in @Regeneron cocktai

FTH_Buddy_Falcon

francesmiddlet2

Given that a percentage (8%-https://medium.com/medical-myths-and-models/the-human-genome-is-full-of-viruses-c18ba52ac195) of our own DNA is virus-based & viruses are VERY adaptable in that they MUTATE FREQUENTLY (https://www.sciencedire

Emily's Entourage

EmilysEntourage

The @US_FDA expanded eligibility for @VertexPharma CFTR modulators to >600 ppl w/certain rare #cysticfibrosis mutations. This is BIG NEWS for 2 reasons.https://news.vrtx.com/press-release/vertex-announces-fda-approvals-trikafta-elexacaft

Eric Feigl-Ding

DrEricDing

Breaking—UK VARIANT MAPPED:We have now a detailed map of the likely spread of the VUI-202012/01 #SARSCoV2 variant among *63,000 positive #COVID19 cases throughout England*!All thanks to a brilliant stroke

Prof Francois Balloux

BallouxFrancois

I felt it may be helpful to provide an update on the new #COVID19 lineages in the UK and in SA that might both be more contagious than any #SARSCoV2

David Ascher

DrDavidAscher

Excited that COVID-3D has been published in Nature Genetics. This is a great piece of work from the group, but led especially @steffportelli @carlosmr12 @elston_neil and Moshe. This work was

Veera M. Rajagopal

doctorveera

Four important papers published in 2020 beautifully demonstrated in what ways PRS will be used in clinic in the near future. A thread. 1. PRS is often seen as a

Dr. Angela Rasmussen

angie_rasmussen

With global spread, national border closures seem like a pretty facile solution to hypothetical more infectious variants that haven’t emerged yet or been imported. Int’l travel isn’t a selection pressure

Vaughn Cooper

vscooper

A long time ago, in a cozy @UofNH lab, @GeiselBiofilm suggested we do a biofilm evolution experiment with P. aeruginosa PA14. To nobody's surprise, the populations diversified, but the extent

Eric Feigl-Ding

DrEricDing

Whoa—Scientists have raised possibility that the increase in transmission is maybe due to kids. A new detail on UK mutated variant B.1.1.7–New strain may make children “as equally susceptible

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