#Genomic

Matt Ridley

mattwridley

Thread on the new strain of SARS2 in the UK.It's more than just a single mutation: 14 non-synonymous changes and several deletions.https://virological.org/t/preliminary-genomic-characterisation-of-an-emergent-sars-cov-2-lineage-in-the-u

Bill Hanage

BillHanage

But I will note that mutations happen all the time. The more infections, the more opportunities to explore the the space of possible mutations. Basically you wouldn't have expected this

Jeffrey Barrett

jcbarret

One of the key questions about the new variant (B.1.1.7) is whether there is conclusive evidence that it is more transmissible. I don't think we are absolutely certain yet, but

Duncan MacCannell

dmaccannell

One important gap in many state and local #publichealth departments -- and in many national programs as well -- is the limited number of staff with deep, practical expertise in

john mcclean : 😷 stay at home 😷

johnmcclean_ie

Manaus has a population of ~2 million.~45,000 are over 70. They have had 4,000 deaths already and are now experiencing a devastating 2nd wave.Ireland has ~450,000 over 70s and the

Anderson Brito

AndersonBrito_

The past two months have been quite imtense: heavy workload with genomic surveillance of SARS-CoV-2 variants.Beyond my amazing collaborators @YaleSPH, I’d like to give a shout-out to those leading key

Houriiyah Tegally 🇲🇺

houzhou

Our report on the genomic characterisation of the first wave of the SARS-CoV-2 epidemic in South-Africa is now out in Nature Medicine, a study which was crucial to confidently describe

Dr. Ali Nouri

AliNouriPhD

1/The UK #SARSCoV2 variant reported to be 70% more transmissible harbors a set of mutations in the Spike protein––the part of the virus that touches the human ACE2 receptor and

Dr Suresh Muthukumaraswamy

DrSureshMuthu

0. Obviously it is not ideal that border/MIQ workers were not being tested. But is this failure to blame for the current outbreak? Some thoughts on the "border worker hypothesis...(might

Vinod Scaria

vinodscaria

Our recent preprint of genetic epidemiology of #immune #escape variants from global #SARSCoV2 genomeshttps://www.biorxiv.org/content/10.1101/2020.12.24.424332v1 A number of genetic variants in #SARSCoV2 are associated with immune escape - a

Kyle Card

KyleJCard

I’m pleased to share our latest preprint on @biorxivpreprint : “Genomic evolution of antibiotic resistance is contingent on genetic background following a long-term experiment with Escherichia coli”https://www.biorxiv.org/content/10.1

Felix Lansing

felix_lansing

I’m happy to share my #PhD work on @biorxivpreprint. We used directed evolution to generate designer recombinases to correct a 140 kb genomic inversion causing Hemophilia A. 1/10https://www.biorxiv.org/content/10.1101/2020.11.02.328013v1T

Marty Chilberg

mchilberg

I'm still long $SGMO and a buyer not seller currently. Here's a tweet stream with my views and why I left the IV board for mental health and the need

Dr. Ali Nouri

AliNouriPhD

1) STUDY: two mutations in SARS-2 are correlated with higher fatality: analysis of 12K SARS-2 genomes identified mutation in ORF1ab protein (aids in RNA replication) and mutation in Spike protein

Reuters

Reuters

A new variant of the pandemic SARS-CoV-2 coronavirus is spreading rapidly in Britain and prompting high levels of concern among its European neighbors. The strain is said to be up

Andy Walker

Andy_Walker

Here are some of key papers, docs, and threads on the emergent variant of SARS-CoV-2 that I've come across. Please do comment with more (1/n) (Not directly about the new

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