1) STUDY: two mutations in SARS-2 are correlated with higher fatality: analysis of 12K SARS-2 genomes identified mutation in ORF1ab protein (aids in RNA replication) and mutation in Spike protein (needed for cell entry) correlate with fatality in nations they've taken hold in...
2) S protein mutation is the famous D614G variant that appeared in Europe and took over and previously thought to increase infectivity ( https://bit.ly/3fUTHcJ ) The new study found that the correlation between mutations and fatality holds even in sub-regions of the US...
2) S protein mutation is the famous D614G variant that appeared in Europe and took over and previously thought to increase infectivity ( https://bit.ly/3fUTHcJ ) The new study found that the correlation between mutations and fatality holds even in sub-regions of the US...
2) S protein mutation is the famous D614G variant that appeared in Europe and took over and previously thought to increase infectivity ( https://bit.ly/3fUTHcJ ) The new study found that the correlation between mutations and fatality holds even in sub-regions of the US...
3) Fatality rates in eastern US (hit by European variant) are higher than western US. Still, correlation isn't causation so more studies needed. If relationship holds, would be one of number of factors, e.g. age distribution, public health measures, etc... https://www.nature.com/articles/s10038-020-0808-9
SARS-CoV-2 genomic variations associated with mortality rate of COVID-

SARS-CoV-2 genomic variations associated with mortality rate of COVID-19

https://www.nature.com/articles/s10038-020-0808-9
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