Farid Jalali MD
farid__jalali
Folks - if your covid patient is doing well respiratory wise but suddenly starts to become delirious and agitated and hallucinate -> tachypnea - it is due to SEROTONIN excess
Read more
on serotonin, SSRIs, serotonin-blockers, and COVID19All causes of ARDS are associated with activation of resident lung platelets and megakaryocytes. The degree to which this activation occurs differs between various etiologies
Read more
Proper attention to š¯—®š¯—¹š¯—¹ aspects of pathology in COVID19, simultaneously, is paramount to proper treatment: pulmonary endothelium plateletsProducts of platelet-endothelial
Read more
I believe we do NOT understand PE pathophysiology. Therefore, we do NOT understand COVID19.Serotonin rules PE cardiovascular changes.Serotonin rules COVID19 pathology.1967 paper:https://www.sciencedirect.com/science/article/abs/pii/00029149
Read more
COVID19 causes FLORID platelet activation, FAR beyond what ARDS typically causes. Platelet hyperreactivity in COVID19 is quantifiably higher than typical ARDS and exorbitantly higher than healthy individuals or admitted inpatients.
Read more
Yes. Platelets are those cells that in turn activate endothelium. There is a billion of these platelets and megakaryocytes PARKED in the lung microvascular space.https://www.biorxiv.org/content/10.1101/2020.11.08.372581v1 And there is an ov
Read more
I refrain from recommending a cocktail, but at 200k cases per DAY now of COVID19, I think it may be time to go ahead:I think folks should consider taking an
Read more
Long haul COVIDIs most likely aMast cell activation syndrome (MCAS)(I think .....) Myocarditis of MCAShttps://www.ahajournals.org/doi/full/10.1161/circulationaha.107.741595 https://www.cell.com/trends/immunology/fulltext/S1471-4906(20)30130
Read more
Pediatric Multisystem Inflammatory Syndrome of COVID19 is also a "platelet hyperactivation syndrome", just like Kawasaki's Disease is.The underlying pathophysiology is:Half of circulating platelet biogenesis occurs in lungs fr
Read more
By continuing to use the site, you are consenting to the use of cookies as explained in our Cookie Policy to improve your experience.