#Sequencing

Dr Emma Hodcroft

firefoxx66

A #SARSCoV2 variant with a combination of mutations in Spike (S13I, W152C, L452R) has been making headlines & twitter rounds today, so - a fresh-from-the-oven S:L452R focal build is

Chris Langmead

chrislangmead

Delighted that our collaborative study on the role of M4 muscarinic receptors in alcohol addiction is finally out in Biological Psychiatry (@els_psychiatry). Major effort by teams at @TheFlorey and @MIPS_Australia.

Trevor Bedford

trvrb

Given that the US has not detected SARS-CoV-2 variant viruses 501Y.V1 or 501Y.V2, what bounds can we place on their current frequency in the US based on sample counts? 1/12https://twitter.com/trvrb/status/1341446447045087232

Andrea Ruggeri

aruggeri_eu

It was fun! I do it to learn more from graduate students' research projects and to push me to think systematically about theorizing. It is my "research gym", the only

JepsonLab_UCL

JepsonlabU

Observation. Since moving into the neurological disease field, I've found that many (reviewers!) feel that animal models need to precisely phenocopy human symptoms to be 'valid'. A brief thread on

Lauring Lab

LauringLab

Excited to share our latest, out in @cellhostmicrobe. Great work by @alvalesano. This was a real team effort with major contributions from @mt2fus @famulare_mike many colleagues from @UVA_ID and @icddr_b

Geoffrey York

geoffreyyork

South African science was crucial in helping UK discover its new variants; but then the UK govt claimed (wrongly) that the SA variant is more transmissible. No evidence to support

Kate

Asilverlining20

Thread: 1) Massive PCR testing campaigns are resulting in the quarantine of healthy individuals, temporary business & school closures, mask mandates, & unnecessary panic and fear. Damage is being done

Dake Kang

dakekang

1/ NEW: During 12 fateful days in January, Chinese authorities failed to report any new coronavirus cases, lulling Wuhan residents into complacency.Why? In part, because of cronyism and secret deals

Bloom Lab

jbloom_lab

We mapped all #SARSCoV2 mutations escaping key antibodies used to treat #COVID19 (https://www.biorxiv.org/content/10.1101/2020.11.30.405472v1). Surprising observations: one amino-acid mutation escapes *both* antibodies in @Regeneron cocktai

The Medical SHO

admit_medics

You’re the medical registrar on-call and receive a call from the psychiatry SHO as a patient has an adjusted calcium of 1.76. This is a 31 year old male currently

Andrew J. Roger

andrewjroger

Long branch attraction explained! Ed Susko and I have been investigating the reasons why long branches tend to attract in phylogenetic analyses. This paper provides new insights into why this

David Ascher

DrDavidAscher

Excited that COVID-3D has been published in Nature Genetics. This is a great piece of work from the group, but led especially @steffportelli @carlosmr12 @elston_neil and Moshe. This work was

The Medical SHO

admit_medics

A 27 year old male presents to ED with myalgia and dark urine. His U&E are through the shoot! Cr 765!!! He’s not passed much urine either. He’s been unwell

Sizwe sikaMusi

SizweLo

In early 2020, a South African company, Conoché Bio-Tech approached the Medical Research Council MRC about a product - a castor oil extract - that could be used as a

Eric Feigl-Ding

DrEricDing

BREAKING—Tracing WH #COVID19: WH blocked tracing but 2 journalists donated samples to epidemiologists. “These mutations [in] these viruses are quite rare in US,” Bedford said. “I am highly convinced that

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