#Novavax

Caroline Coram

CarolineCoramUK

PHARMA: When we have an ‘outbreak’ of something there are usually one or two companies that lead and develop supposedly preventative vaccines. This time round we have every Pharma company

Dr. Ali Nouri

AliNouriPhD

1/Next US Vaccine:@Novavax began Phase 3 Trial. KEY difference: While Moderna/Pfizer deliver genetic material (mRNA) that our cells subsequently turn into Spike protein, #Novavax delivers the Spike protein directly. To

Deep Barot

deepbarot

Important thread on latest developments in #COVID19 vaccine race, thread also breaks down my investment picks as requested. Right now (in the US):1. Moderna- Phase II (Clinical Trials), NIAD partnership2.

Prof Francois Balloux

BallouxFrancois

The recent Novavax vaccine trial reported lower efficacy in its SA arm. This is plausibly caused, at least in part, by the high frequency of the B 1.351 lineage in

Paradigm Shift Platforms

Shift_Platforms

@Forbes - maybe you need me to write the health science articles?https://www.forbes.com/sites/greatspeculations/2021/02/01/novavaxs-highly-effective-vaccine-could-be-a-game-changer/?sh=7f747a03cfe9Enlighten me how preventing literally only

Eric Topol

EricTopol

For evaluating the vaccine trials (and any trials), it's important to look at the number of endpoints and their severity.The J&J trial has the same number of endpoints as @Pfizer/

HermisHuman

Andy_Redd

The South African serology results from the @Novavax vaccine trial drastically need more clarification. From the protocol posted in their Phase 2 results it appears they used an in-house ELISA

Tyler Shandro

shandro

Having a Canadian-made solution to vaccine production is a positive step forward, but having to wait until the end of 2021 isn’t going to cut it. Canadians, including Albertans, need

Anupam Singh

anupampom

Very important study with implications 4 India1. Novavax Vaccine (being manufactured by COVOVAX by Serum Institute) has 89% efficacy in UK trial ( normal and UK Variant ) n 60%

Eric Feigl-Ding

DrEricDing

Worrisome discovery—Among placebo group for Novavax’s vaccine in South Africa: people with prior #COVID19 infections appeared just as likely to get sick as people without prior infections—means past infection wasn’t

Bijan Salehizadeh

bijans

Spent some time today going through late-phase protocols and reported data for major COVID-vaccine programs trying to understand primary/secondary endpoint definitions. Summary: great consistency in definitions of mild/moderate/severe but..

Prof. Akiko Iwasaki

VirusesImmunity

How well do various vaccines reduce severe COVID disease & death? Awesome @YaleMed students, @dariusdariusdar, @ChaneyKalinich, @Larson_HaleighT & Caroline Valdez put together summary tables from vaccine trials. Remarkable ability o

Allen Cheng

peripatetical

As overall infection was reduced, this would suggest that the AZ vaccine does reduce infectiousness so some degree. But even if all adults were vaccinated, it probably wouldn't achieve herd

Matthew Herder

cmrherder

This is an accessible primer on the steps involved in, + challenges that need to be overcome in manufacturing mRNA vaccines by @Dereklowe https://blogs.sciencemag.org/pipeline/archives/2021/02/02/myths-of-vaccine-manufacturing HT @SarahKarl

Thomas Christie Williams

Williams_T_C

what a difference a month makes in a pandemicDec '20: lab studies show potential for SARS-CoV-2 mutations to impact antibody neutralisationJan '21: clinical trials @Novavax & @JNJGlobalHealth show 501Y.V2 appears

Drew Armstrong

ArmstrongDrew

There were two VERY big pieces of vaccine news out in the last 24 hours:1)J&J's vaccine (one shot, easier to store) had 66% efficacy at preventing moderate/severe infections. 2) Novavax

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