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Eric Topol
EricTopol
1. Asymptomatic #SARSCoV2 carriers after vaccines, as aptly drawn by @nataliexdean (adapted @TheEconomist) Even w/ the most highly effective vaccines (below), there'll likely be carriers, who can transmit, because shots
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1. The B.1.1.7 variant could prove to be our last major obstacle to achieving containment of the virus in the US. But it isn't getting enough respect. Many states are
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From serology studies it is estimated that 80 to 100 million Americans have had covid-19 infections. New data from @florian_krammer and colleagues suggests that, with + antibody testing, 1 dose
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For evaluating the vaccine trials (and any trials), it's important to look at the number of endpoints and their severity.The J&J trial has the same number of endpoints as @Pfizer/
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Back in September, we wrote a @nytopinion on the need to focus on severe infection events prevented by Covid-19 vaccineshttps://www.nytimes.com/2020/09/22/opinion/covid-vaccine-coronavirus.htmlYesterday JNJ presented their Phase 3 data stre
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Big news: The JNJ vaccine results of 44,000 Phase 3 trial, a single dose. Overall 66% efficacy, with the contrast of 72% in US but 57% in South Africa, confirming
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1. A year ago the first person with asymptomatic covid was documented. My colleague @danieloran culled the data from 61 studies, 1.8 million people to determine how often this occurs.
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What is we were immunoassay-guided for who to give vaccines, whether the vaccine was effective, when 1 dose was enough?Just now, 10 days after my 2nd dose vaccine, I had
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1. If you thought yesterday's more than 4,400 deaths will be the worst of the American pandemic, or the previous >300,000 cases in a day, you're not paying attention. We're
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Why it is time (never too late) to get super-serious1. Holiday surge after holiday surge is small potatoes compared with a superspreader strain. B.1.1.7 is here,
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If you want to know about #SARSCoV2 as it started and where it is going, you talk to @edwardcholmes, a leading evolutionary virologist @Sydney_Unihttps://www.medscape.com/viewarticle/943251 @Medscape video and transcripta /1
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Connecting the dots between RSV, F, erection, S, and 2P's 1. The @McLellan_Lab work on RSV virus to stabilize the F protein (which may lead to successful vaccines)From https://www.newyorker.com/magazine/2021/01/04/the-plague-year @NewYo
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