#Efficacy

David Benkeser

biosbenk

Why is considering a pivot to half-dose regimen different than proposed UK dosing strategy? We will have a rigorous analysis of correlates data to help inform the decision.https://twitter.com/nataliexdean/status/1345860364202876928 Correlat

Dr. Angela Rasmussen

angie_rasmussen

@JNJNews vaccine results are in! While not as efficacious as Pfizer or Moderna it’s still great news—it was 85% efficacious at preventing severe disease requiring hospitalization. Not a “knockout punch”

covid19indiaorg

covid19indiaorg

The expert committee of CDSCO met on 30/12, 01/01 and 02/01 to deliberate on accelerated approval of vaccines. Recommendations made on each day have been officially published. In this thread,

Rajeev Venkayya MD

rvenkayya

THREADHow were the first #CovidVaccines developed in less than a year without cutting corners?The vast majority of vaccine development time is spent *preparing for* Phase 3: the final large-scale, costly,

Andrew💙Croxford

andrew_croxford

".. while measured neutralising antibody titres generated by vaccination with ChAdOx1 nCoV-19 vaccine are lower for the B.1.1.7 lineage, clinical efficacy of the vaccine against symptomatic COVID disease is similar

Eric Feigl-Ding

DrEricDing

DIFFERENCE A VARIANT CAN MAKE: Early in the Oxford-AstraZeneca’s South Africa trial, before #B1351 variant became dominant, the AZ vaccine had a great efficacy of 75% risk reduction of

Pfluft

PloederlM

1/ Our new paper about the minimal important difference (MID) of antidepressants (AD). Because there is a paywall, here the main findings in a thread.https://ebm.bmj.com/content/early/2021/02/15/bmjebm-2020-111600.full 2/ First of all, Mich

Nancy Baxter MD PhD

enenbee

This review of vaccination of COVID19 by Prof Raina Macintyre @KirbyInstitute is required viewingWell worth 34 minutes of your time, but watch at 1.75 speed if you are in a

Hilda Bastian, PhD

hildabast

Phase 3 trial for Sputnik V results landed!To keep in mind: randomized 3 to 1 (not half in vax group, half placebo). It's a pair of vaccines, 1 shot of

Hilda Bastian, PhD

hildabast

It's on the agenda this week: possibly a decision on the Oxford/AstraZeneca vaccine from EMA's (Euro drug regulator) Human Medicine Committee? Applicants will be questioned at the meeting.(EMA process steps

Anupam Singh

anupampom

It is so sad when academics use observational studies and self-promotional press conferences to make statements about efficacy of drugs ,in the process confusing general public, media and needlessly politicising

Florian Krammer

florian_krammer

1) This morning, I shared an enthusiastic tweet about Pfizer's interim results with their COVID-19 vaccine. Let me explain here why am I am so enthusiastic, how the road to

Jaimie Ding

j_dingdingding

So my mom found this article and was panicking - because it said the Pfizer vaccine “was 74.4% effective in Asian Americans” without any explanation or note. This is /extremely

Dvir Aran

dvir_a

How effective are the COVID-19 vaccines? Israel was early to vaccinate its population (~1/3 of pop now with the @Pfizer @BioNtech vaccine) and real-wold data is starting to accumulate. However,

Fionna O'Leary, 🕯🇪🇺

fascinatorfun

Thanks for this incredibly helpful analysis @dgurdasani1 Two questions. 1/ Does this summarise the AZ published data :The plan is to extend the time interval for all age groups despite

Hilda Bastian, PhD

hildabast

Large phase 2 trial of Novavax vaccine in South Africa reportedly has data, reporting soon. Minimum of 3,000 people (up to 4,400), mostly HIV-neg but with 240-person HIV-positive group. Biggest

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