#Dose

🌞 Sol Brah 🌞

SolBrah

Minimum Effective Dose vs. Maximum Tolerable Dose in LIFTING (THREAD)Minimum effective dose is the minimum input necessary to attain a desired result.Maximum tolerable dose is the maximum input a system

𝙀𝙡𝙞 𝙋𝙚𝙧𝙚𝙣𝙘𝙚𝙫𝙞𝙘𝙝 🤚 🧼😷

eliowa

Re: AstraZeneca-University of Oxford vaccineOne word could explain the differential results: BlindingBlinding is allocation concealment in a randomized trial, such that the recipient of the vaccine (and others) don't know

Alex Berenson

AlexBerenson

1/ @cdcgov has released its updated batch of reported Covid vaccine side effect data, through Jan. 8, when roughly 6.6 million doses had been administered. And it is... not good.Reported

Tim Colbourn

timcolbourn

This is a difficult decision. As @CMO_England says, delaying 2nd dose should save more lives though given: 1. Virus is out of control2. Bottlenecks mean more people won’t be vaccinated

Yardley Yeadon

MichaelYeadon3

Combining vaccines is disturbing. It might make sense in one example. I’ve learned that two doses of the AZ vaccine sometimes don’t work optimally because, after the first dose, the

Dr. Birinder Narang MBBS (Hons), CCFP

DrBirinderSingh

1/ Takeaways from #COVID19BC update today:3 reporting periods (Fri-Sun):1475 new cases in BC with 49.9% in @FraserhealthWhile cases are still highest in FH, it is heartening to see the regional

Shehab Khan

ShehabKhan

Latest scientific data on a single dose of Oxford vaccine finds: - Vaccine efficacy 76% from day 22 to day 90.- 100% effective at stopping hospitalisations from day 22 to

Ronen▼.com

RonenV

Ok, I wasn't going to say anything about this, but it's clear that this is accidentally misleading people in a way that may cause more covid infections: "Pfizer claimed trials

Dr. Angela Rasmussen

angie_rasmussen

Thus I'd rather emphasize the additive nature of risk reduction. For aerosols, droplets, or fomites, people should implement as many of the following measures as possible:-Physical distance-Avoid crowds-Avoid indoors/enclosed spaces-Mas

Eric Topol

EricTopol

From serology studies it is estimated that 80 to 100 million Americans have had covid-19 infections. New data from @florian_krammer and colleagues suggests that, with + antibody testing, 1 dose

Dr Michelle Ananda-Rajah

rajah_mich

There are a lot of stats re efficacy flying around for the AZ vaccine. Lets go thru them:-70.4% is a pooled estimate from the low dose & standard dose groups,Dec

David Benkeser

biosbenk

Interesting thread on single-dose trials. Worth reading to hear from some real public health leaders and Nate Silver.Unfortunately, I don’t see a way forward for new single dose efficacy trials

Eric Feigl-Ding

DrEricDing

NEW—Fauci says the first single-dose #COVID19 vaccine by Johnson & Johnson could get emergency approval in just two weeks. The J&J vaccine has field advantage in mass inoculations in being

Ed MD

notdred

My take is: I don’t think Moderna or Pfizer actually believe their vaccine will have durable efficacy after one dose. Exactly this:https://twitter.com/jallepap/status/1343318430821314568?s=21 One problem with pushing for a large single-do

Amberite's Eschatological Cabaret 🌈⛥✡⛧they/them

outliersgeorg

The proportion of COVID deaths that's older folks and folks with underlying conditions does Not, in any way, make it OK that people are dying, but it IS probably a

Christina Pagel

chrischirp

THREAD ON UK VACCINATION PROGRAMME: TLDR: At 3 mill doses/week expect a big slowdown in *first* doses in April/May. But then summer ramp up to vaccinate all adults by early

By continuing to use the site, you are consenting to the use of cookies as explained in our Cookie Policy to improve your experience.