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#Novavax
Sam Freedman
Samfr
This is superb news. A 4th working vaccine and UK has ordered 60m doses.https://twitter.com/BBCFergusWalsh/status/1354899361365422085 J+J reporting next week. That will hopefully give us 5. Hugely important in speeding up the
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Florian Krammer
florian_krammer
1) The low efficacy of the Novavax vaccine candidate against the B.1.351 is concerning. However, the data is also reassuring in many ways. First, the vaccine itself worked very well
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A Marm Kilpatrick
DiseaseEcology
Novavax has shared prelim efficacy data by press release:https://ir.novavax.com/news-releases/news-release-details/novavax-covid-19-vaccine-demonstrates-893-efficacy-uk-phase-390% overall, 50% in S Africa (60%) in HIV-.But there's more.
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Mia Malan
miamalan
[Thread] 1.What does #Novavax #CovidVaccine results mean for SA? The jab has 49.4% efficacy in SA (UK: 89%). The #501yv2 variant likely had an impact on SA's results: participants were
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Meg Tirrell
megtirrell
Novavax gives us first vaccine efficacy data we’ve seen against B117 (UK) and B1351 (South Africa) variants, from trial results just reported.In UK the news is good: 89% efficacy in
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Jamie Triccas
TricckyLab
1) With the release of Novavax data we are starting to get a good handle on how the level of immunity correlates with vaccine efficacy. So can use this to
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Shane Crotty
profshanecrotty
1/ Novavax UK first: ~90% protection again any symptomatic COVID-19. And that high level of protection was accomplished under conditions of very intense community transmission in the UK, which is
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Dr Zoë Hyde
DrZoeHyde
(1/7) Spectacular news from Novavax. The efficacy of their vaccine matches Pfizer & Moderna, but it doesn't have the same ultra-cold storage requirements. UK phase 3 trial results:95.6% original COVID-1985.6%
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Dr. Angela Rasmussen
angie_rasmussen
Good and bad news about the Novavax protein subunit vaccine. 90% efficacy in the UK, but only ~50% in South Africa, largely because of the B.1.351 variant. Hopeful news too:
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Hilda Bastian, PhD
hildabast
Large phase 2 trial of Novavax vaccine in South Africa reportedly has data, reporting soon. Minimum of 3,000 people (up to 4,400), mostly HIV-neg but with 240-person HIV-positive group. Biggest
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Kenneth Macdonald
macdonke
Some other countries are not rushing to deploy a vaccine. UKG is having to because its test, trace and isolate system has been dismal so far. That said, vaccines are
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Jamie Triccas
TricckyLab
Really interesting data coming out of latest report on Oxford/AZ vaccine efficacy trials (another one!).A little on this.#COVID19 #CovidVaccine https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3779160 What did they find?Trial looked at p
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Eric Topol
EricTopol
Back in September, we wrote a @nytopinion on the need to focus on severe infection events prevented by Covid-19 vaccineshttps://www.nytimes.com/2020/09/22/opinion/covid-vaccine-coronavirus.htmlYesterday JNJ presented their Phase 3 data stre
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Ashish K. Jha, MD, MPH
ashishkjha
Feeling pessimistic about COVID & 2021? Don't!I'm not. Here's whyWe'll likely have about 400M doses of Moderna/Pfizer by end of JuneEnough to vaccinate 80% of adultsAnd that means a much
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Max Kennerly
MaxKennerly
FYI, if you see declarations about new COVID variants evading immunity:1) this isn't about the vaccines, which work against the variants2) the issue is naturally acquired immunity, based on placebo
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James Krellenstein
jbkrell
So the @Novavax results showing 90% vs. 49% efficacy make the results of the @JNJNews results even more exciting. JNJ is evaluating their Ad26 vaccine in S Africa as
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