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Michael Mina
michaelmina_lab
On TTI as a control measure: Early 2020, we said contact tracing would not control community spread against #COVID19 once cases got high Yet when cases got high, it was
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NEW RESEARCHKnowing if #COVID19 cases are going up v down is needed for decision making but changes in testing make it difficult to knowWe found Instead of case counts, the
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The new variant B.1.351 is evading immunity, infecting ppl already vaccinated w AZ vaccineI’m concerned for the others too since all have very similar design against original SpikeThis should be
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Short thread:Cases are starting to plummet quickly. This isn’t from vaccines (yet). Possible we may be starting see a combination of seasonality on our side and likely seeing herd effects
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RAPID ANTIGEN TESTS WILL DETECT THE VARIANT STRAINS(Has quickly become the most frequently asked question....The epitopes targeted are not under selective immune pressure) A bit more nuance. Most rapid antigen
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Important: on the resurgence of SARS-CoV-2 in a place where herd immunity was already attained.The authors lay out 4 reasons:1) didn’t actually attain herd immunity2) waning immunity3) new strains evading
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Short On mutant strains emerging:It’s a new virus - not in an optimal state upon “birth” as it leaped into humans.Has so much room to grow and ‘learn’Increases in transmission
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Rapid Antigen tests for #COVID19 in UK are working! Purpose is to rapidly identify infectious people - that is exactly what they are doing!And doing it very well!With an R=1.4,
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PCR positivity detected after symptom onset rarely reflects replicating likely contagious virus.PCR remains + for so longIn @NatureComms van Kampen et al. show this well. Look at how few PCR
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Apparently I cannot say this loudly enoughThe recent @bmj_latest articles by @deeksj et al deriding Rapid Ag Innova Tests are simply WRONGThey simply do NOT appropriately interpret Ct values &
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Will delaying #COVID19 vaccine doses cause vaccine immune escape?This nice article misses an extremely important part - that unvaccinated ppl too have so called “partial immunity” while infected.Escape from immunity
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CLARIFICATION: Much confusion about rapid antigen testsALL evidence - when evaluated appropriately! - shows these are VERY good at detecting infectious virus• ~100% if used frequently• >95% for single samples with high,
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