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will present work from ERICA-SA – Evolving Risk Factors for Cancers in African Populations where I’m a proud collaborator
Studying breast, oesophageal squamous & cervical cancer.
Funded by South Africa MRC @MRCza, Newton Fund @The_MRC /1 https://www.samrc.ac.za/intramural-research-units/evolving-risk-factors-cancers-african-populations-erica-sa
will present work from ERICA-SA – Evolving Risk Factors for Cancers in African Populations where I’m a proud collaboratorStudying breast, oesophageal squamous & cervical cancer.
Funded by South Africa MRC @MRCza, Newton Fund @The_MRC /1 https://www.samrc.ac.za/intramural-research-units/evolving-risk-factors-cancers-african-populations-erica-sa
The ERICA-SA project looks at genetic susceptibility, lifestyle risk factors and infectious agents, using 20k African cancer patients from the Johannesburg Cancer study.
Aims – do good science, enhance research capacity in S Africa.
The best study logo ever: /2
Aims – do good science, enhance research capacity in S Africa.
The best study logo ever: /2
ERICA-SA Results will be presented at the Inaugural @AORTIC_AFRICA Cancer Genomics Conference, Feb 18-19, 2021.
African genomic diversity. A roadmap to global equity in cancer control #AfricanCancerGenomics
https://aortic-africa.org/cancer-genomics-conference/
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African genomic diversity. A roadmap to global equity in cancer control #AfricanCancerGenomics
https://aortic-africa.org/cancer-genomics-conference/
/3
Wenlong Carl Chen, @Phried_fonix @SBIMB, presents his #GWAS of esophageal squamous cell carcinoma – first such study in Africa, where this cancer has a high prevalence. Trans-ancestry meta-analysis of African and Chinese GWAS ids 3 hits /4
Mahtaab Hayat @mahtaabhayal has been performing the first #breastcancer GWAS in South African black populations. Looking for novel loci and transferability across populations. /5
Abram Kamiza has performed a GWAS in SA black populations with cervical cancer, looking at host genetic factors in addition to HPV infection.
GWAS finds several associations including HLA-DQA1 /6
GWAS finds several associations including HLA-DQA1 /6
Genotyping on the @H3Africa chip at @SGDPCentreKCL. Challenging QC, imputation: limited African Genome reference panel and rich diversity across short geographical distance.
Thanks to skilled @SBIMB1 bioinformaticians for sharing analysis expertise /7
Thanks to skilled @SBIMB1 bioinformaticians for sharing analysis expertise /7
The National Cancer Registry South Africa, lead by @ElviraSingh, home of the Johannesburg Cancer Study is an amazing resource for genetics, epidemiology and treatment studies. /8
https://www.sciencedirect.com/science/article/abs/pii/S1877782120300357?via%3Dihub https://www.nicd.ac.za/centres/national-cancer-registry/
https://www.sciencedirect.com/science/article/abs/pii/S1877782120300357?via%3Dihub https://www.nicd.ac.za/centres/national-cancer-registry/
ERICA-SA is an international collaboration – thanks to Chris Mathew, @FreddySitas @ChantalBabb @ElviraSingh, Debbie Bradshaw, Jean-Tristan Brandenburg and many more team members 9/end
