#Mutation

Still digesting #bladdercancer trials at #GU21. QUILT 3.032 trial https://clinicaltrials.gov/ct2/show/NCT03022825 testing #N803 in BCG-unresponsive CIS was an important result. Safety data appropriate for intravesical therapy – and CR rat
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Why it is time (never too late) to get super-serious1. Holiday surge after holiday surge is small potatoes compared with a superspreader strain. B.1.1.7 is here,
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Saw this paper by way of @apoorva_nyc: "Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants"https://www.biorxiv.org/content/10.1101/2020.07.21.214759v1.abstractMy instinct is to expect any preprint on this top
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This is a very major concern. Why reducing community transmission is so important. The more virus circulating, under immune pressure, the more likely it is to mutate, evolve and change.https://www.telegraph.co.uk/news/2020/12/18/exclusive-b
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We interviewed @SteveFDA and Peter Marks @US_FDA about the new vaccineshttps://www.webmd.com/coronavirus-in-context/video/whyte-topol-hahn-marks w/ @drjohnwhyte @WebMD @MedscapeKey points that we covered:1. The EUA tightening that got the t
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A new strain of #COVID19 has evolved in England. It's 70% better at spreading from person-to-person. This is our punishment for not eradicating the disease over the summer. We gave
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$VXRT has positioned themselves really well as a second generation oral vaccine that can fill in the gaps of these more fragile injectables like $PFE and $MRNA. This new article
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The British government was blindsided by a new strain of coronavirus, and again by the world’s response. The inside story of how Johnson was forced into action. By @Steven_Swinford (1)https://www.thetimes.co.uk/edition/news/a-warning-a-ca
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BAD NEWS: 2 cases of a new "more transmissible" #coronavirus variant linked to #SouthAfrica identified in the UK.This new variant appears to have *mutated further* than the new B.1.1.7 variant
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Thread: Dalits in US tech companies say caste discrimination from upper castes at work is rampant. I explore the manifestation of India’s centuries-old caste system in US MNCs, in the
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1/ People always get hung up on the word "binary" in relation to biological sex. Sex is still binary even if some people may be truly sexually ambiguous and cannot
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As Victorians breathe a well deserved sigh of relief this weekend, having smashed 2nd wave in world beating fashion, I wanted to talk about the way simplified media narratives have
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Read this lucid wonderfully readable article by ⁦@liammannix⁩ UK variant (B.1.1.7) South African variant (B.1.351) Brazilian variant (P.1)* Difference between: Mutants, Variants, Strains* Spike Protein mutations* Vaccines efficacyhttps
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In the original 60s run, the implication is mutation is caused by nuclear radiation. In #1 Xavier says he believes he is the first mutant, and his parents worked on
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#FDA recently approved #pembrolizumab- a tissue agnostic indication in metastatic tumors with high #TMB (>10 mut/MB) using Foundation One Dx companion diagnostic test. I want to share a tweetorial on
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1) Montreal public health authorities revealed on Wednesday that the super transmissible B117 variant is circulating a lot more in the city than previously known, triggering massive #COVID19 screening in
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