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#B1351
Eric Feigl-Ding
DrEricDing
BREAKING—new #B117 variant & vaccine data from research lab shows mutations in B117’s spike protein yields a ~3.8x reduction in efficacy of vaccine-generated neutralization antibodies compared to wildtype (WT)
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Eric Feigl-Ding
DrEricDing
NOT GOOD—so it seems government researchers have discovered that the already more contagious #B117 has further acquired the other troublesome E484K mutation seen in #B1351 & #P1 variants—in 11
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Rommie Amaro
RommieAmaro
In a new @biorxivpreprint with @McLellan_Lab @ltchong @Terrasztain @LCasalino88 @fiona_chembot @JoryGoldsmith, we show how a glycan gate (at position N343) controls the opening of the #SARSCoV2 spike protein #GlycanGate #glycotimehttps://ww
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Deepti Gurdasani
dgurdasani1
Concerning data from PHE today suggesting that sequencing shows that there are 11 cases of the UK variant (B117) identified that also have the E484K mutation (the one found in
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Eric Feigl-Ding
DrEricDing
SURGING #B117 WITHIN US—growing 7% per day, doubling every 9.8 days nationally, & expected to become dominant by March 23rd. It is surging fastest in Florida—doubling every 9.1 days. Scientists
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Aaron Derfel
Aaron_Derfel
1) While other provinces are providing detailed breakdowns on the number of #COVID19 variants, confusion and a lack of information persist in Quebec about the more transmissible strains. In this
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Eric Feigl-Ding
DrEricDing
FANTASTIC NURSING HOME NEWS—Eli Lily’s monoclonal antibody drug can lower the risk symptomatic #COVID19 by 80% when used preventively among nursing home residents. Cuts risks overall by 57% among both
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Eric Feigl-Ding
DrEricDing
Immunocompromised 45 year old suffered from #COVID19 for 155 days before he died. The virus was changing very quickly inside the man's body—it acquired a big cluster of >20 mutations—resembled
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Eric Feigl-Ding
DrEricDing
WORRISOME MATH—#B117 variant is so crazy: what happens if there are just 10 cases now, & new #B117 has 50% transmissibility? 1000+ daily cases on Mar232000+ daily cases on
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Cornelius Roemer
CorneliusRoemer
Erstmals relativ verlässliche Berechnung des Varianten-Anteils in Deutschland möglich, weil @Koeln ALLE Fälle auf Varianten prüft.#B117-Anteil: 9% (±3%)#B1351-Anteil: 5% (±2%)Berechnung:Köln hatte in letzten 7T 880 neue Fälle, 80 ma
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Eric Feigl-Ding
DrEricDing
Concerning—new data shows the more contagious #B117 variant is growing so quickly in Florida—now almost 10% of all #COVID19 case. California only ~2 weeks behind. Surge of #B117 may yield
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Eric Feigl-Ding
DrEricDing
JUST ONE PERSON—UK scientists think one immunocompromised person who cleared virus slowly & only partially wiped out an infection, leaving behind genetically-hardier viruses that rebound & learn how to
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Eric Feigl-Ding
DrEricDing
“There’s clearly something going on with this mutation”: 7 striking new converging variants with same #677 mutations suddenly found. Experts across US independently found them & are worried—all 7 changed
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Eric Feigl-Ding
DrEricDing
BREAKING—A new #SARSCoV2 variant (aka B.1.1.248) identified by Japan in pax from Brazil . This new one has both the more infectious N501Y mutation (not affect vaccine), as well
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Eric Feigl-Ding
DrEricDing
NEW VARIANT—New California variant CAL20C has recently found in over **half** of all samples in Los Angeles #COVID19 cases, & ~20-30% across CA. “I’m decently confident that this is a
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Whitney R. Robinson
WhitneyEpi
Of the threads I’ve read exploring the causes of falling rates of #SARSCoV2 infections (and hospitalizations and deaths), I like this one best 1/https://twitter.com/nataliexdean/status/1362100680492601350 2/ Even if Rt transmission rates
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