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#ARDS
Joanna Poole 💙
Jopo_dr
Little history of Lung Protective Ventilation [LPV] Ventilation first became widespread in the polio pandemics of the 20th century. Prior to that it has consisted more of using bellows to
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ChaiCoffsKey
ZTan14377
Ok,social scientists, time to sit down, shut up and listen.1)DEXAMETHASONE IS A STEROID THAT IS USED TO TREAT THE HAVOC THAT THE CORONAVIRUS WREAKS ON THE IMUNE SYSTEM KNOWN AS
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Robert Dickson
robertpdickson
[thread] The paradox of treating ARDS is this: because we don't have a drug to reverse lung injury, we provide supportive care with two therapies - oxygen and mechanical ventilation
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Michael Griksaitis
MJGriksaitis
‘How do I manage refractory hypoxaemia?’ Is the question to be answered by @ICheifetz Firstly - what is refractory hypoxemia? In general: failure to maintain saturation’s >88%#WFPICCS20 #PedsICU The PALICC
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Dr. Ali Nouri
AliNouriPhD
1/SARS-CoV-2 in aerosols: from dispersion in air, to inhalation and disease: (a) while large drops (green) are ballistically and fall, smaller ones (red) can remain buoyant; (b) Droplets evaporate to
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John West 🕯💙
JohnWest_JAWS
Let's be clear - The UK study trial of Dexamethasone is important.The early ventilation in Covid (as used in ARDS) produced bad outcomes - which is counter intuitive This is
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Andy Conway Morris 😷🧼🇬🇧🇪🇺
andymoz78
So the #RECOVERYtrial RECOVERY dexamethasone study has been released as a preprint, although one should be careful of pre-prints, the team delivering this & the nature of the (non-commercial) study
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The Phlegmfighter
phlegmfighter
#overdrive #ventilation improved #oxygenation in this #COVID #ARDS patient today by 10% #SpO2 w/o any change an #FiO2 or #PEEP. Ask me how or take a stab yourself with these
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Brent O'Carrigan
brentocarrigan
Short thread on evidence for steroids in #ARDS or lung crit care before #RECOVERYtrial: some discussion on #MedTwitter that "steroids make everything better" or "we already know steroids help" that
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Robin Monotti
robinmonotti
1. "Speaking through some masks dispersed largest droplets into a multitude of smaller droplets..smaller particles are airborne longer than large droplets (larger droplets sink faster), a mask might be counterproductive."https://a
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SeedFirst
_seedfirst
Lowest float COVID-19 plays I've found from searching trial/fda/news daily:< 5m $ABIO $INMB $EDSA $BLPH $ARDS< 10m $ACER $IMUX $POAI $BMRA $ATOS $PDSB $CLBS< 20m $SINT $KLDO $XAIR $CEMI $EVLO
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Lane Fox Research Unit
LaneFoxResearch
Really looking forward to the next session on "Critical Illness: What, Who, Why and How to Treat"World class, inspirational speakers, chaired by our magnificent Dr Michelle Ramsay and @DrIntensive #BTSWinter
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Dr. Nahid Bhadelia
BhadeliaMD
My thoughts on RECOVERY trial results (not data). First, here is the methodology & results.-Large (11k) trial testing multiple treatment arms-2104 randomised to dexamethasone 6mg/d for ten days and compared
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Mosa AlShabeeb
Mosapositive
How to choose your optimal PEEP?Have a seat, bring your coffee and let’s move on.N.B: this is not a reference, it is just flashes to what you need to know#MedTwitter
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Nicolas Merke
NMerke
1/4 One of our biggest issues in #echofirst is foreshortening. Overcoming by trying to put probe downw ards, respiratory efforts by patient also helpful, than better extension of LV but
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Simon Cleary
Simon_J_Cleary
New research out in @JClinicalInvest! Critical roles for endothelial antigen and complement in a model of antibody-mediated lung injury + imaging of #ARDS lung pathology initiation #InMice @UCSF @immunox. Free
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