Really looking forward to the next session on "Critical Illness: What, Who, Why and How to Treat"

World class, inspirational speakers, chaired by our magnificent Dr Michelle Ramsay and @DrIntensive

#BTSWinter

Immunomodulation in #sepsis @msh_manu

Not all sepsis deaths "attributable" or "preventable"
Infection v sepsis
Dysregulatory immune responses
T-cell exhaustion: ≠ respond to antigen challenge
risk bacterial inf & dormant inf reactivation hosp LOS/death
#BTSWinter

Pharmacotherapy for ARDS @charlot_summers

ARDS not a disease; heterogenous population
Need to ID mechanisms & targeted therapies
Hyper/o inflamm phenotypes? Mortality & treatment response differences
EMINENT-ARDS to ID and validate subtypes

#BTSWinter

Prof John Simpson defining ventilator-associated pneumonia

Clinical tools, CXR, diagnostic criteria limited utility
S.aureus most common (≠pseud)
Inappropriate ABx use
ETA in IMV likely high false, CT req transfer & non specific, ?US
Future: BAL, omics?

#BTSWinter

As expected, fantastic, educational and accessible talks, great audience questions and chairing.

We #ICU & #Respiratory clinical and academic collaborations, thanks to all

#BTSWinter