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Really looking forward to the next session on "Critical Illness: What, Who, Why and How to Treat"
World class, inspirational speakers, chaired by our magnificent Dr Michelle Ramsay and @DrIntensive
#BTSWinter
World class, inspirational speakers, chaired by our magnificent Dr Michelle Ramsay and @DrIntensive
#BTSWinter
Immunomodulation in #sepsis @msh_manu
Not all sepsis deaths "attributable" or "preventable"
Infection v sepsis
Dysregulatory immune responses
T-cell exhaustion: ≠ respond to antigen challenge
risk bacterial inf & dormant inf reactivation hosp LOS/death
#BTSWinter
Not all sepsis deaths "attributable" or "preventable"Infection v sepsisDysregulatory immune responsesT-cell exhaustion: ≠ respond to antigen challengerisk bacterial inf & dormant inf reactivation hosp LOS/death#BTSWinter
Pharmacotherapy for ARDS @charlot_summers
ARDS not a disease; heterogenous population
Need to ID mechanisms & targeted therapies
Hyper/o inflamm phenotypes? Mortality & treatment response differences
EMINENT-ARDS to ID and validate subtypes
#BTSWinter
ARDS not a disease; heterogenous populationNeed to ID mechanisms & targeted therapiesHyper/o inflamm phenotypes? Mortality & treatment response differencesEMINENT-ARDS to ID and validate subtypes#BTSWinter
Prof John Simpson defining ventilator-associated pneumonia
Clinical tools, CXR, diagnostic criteria limited utility
S.aureus most common (≠pseud)
Inappropriate ABx use
ETA in IMV likely high false
, CT req transfer & non specific, ?US
Future: BAL, omics?
#BTSWinter
Clinical tools, CXR, diagnostic criteria limited utilityS.aureus most common (≠pseud)Inappropriate ABx useETA in IMV likely high false, CT req transfer & non specific, ?USFuture: BAL, omics?#BTSWinter
As expected, fantastic, educational and accessible talks, great audience questions and chairing.
We
#ICU & #Respiratory clinical and academic collaborations, thanks to all 
#BTSWinter
We
#ICU & #Respiratory clinical and academic collaborations, thanks to all #BTSWinter
