Global health expenditure is rising dramatically and is expected to reach 10 trill. USD by 2022.

Here is a thread on the major issues of the current healthcare industry and finally three companies that are aiming to solve them through disruptive technology.

$SDGR $CMLF $CLNK

In 2015 there were approximately 900m people over the age of 60. This number is forecasted to increase to more than 2b people in 2050. Simultaneously the frequency of chronic diseases such as cancer, heart disease and diabetes are sadly increasing as well.

This has led to huge investment sums to improve and enhance health systems that burden public expenditure. Below is a graph showing a global comparison of national health expenditure as a percentage of GDP between 1975-2018.

The issue is that costs of developing a new drug have increased significantly in recent years and the ROI of drug development has decreased accordingly. Despite the rising costs, there was no significant growth in the number of drugs authorized, which generally remained constant.

I think these challenges obligate health systems and the pharma industry to undergo drastic changes, to identify and develop precise, personalized and effective medical solutions.

The genomic revolution, the dramatic decline in the cost and increased speed of DNA sequencing alongside Artificial Intelligence and Big Data are today leading to the development of advanced diagnostic technologies that are based on protein-level, genomic and clinical data.

We already have various companies aiming to offer a new multidisciplinary healthcare industry that is based on connecting various technologies from the fields of biology and engineering.

Below is a very quick breakthrough of three of my favourites:

Cellink Life Sciences $CLNK-B

Aiming to “Create the future of medicine”, Cellink have focused on the three application areas that are essential to cell culturing: Bioprinting, Analysis, Biosciences and Industrial Solutions.

At the same time, they have made significant progress in research and development and have acquired complementary technologies within these fields to provide scientists with complete workflows.

Schrödinger Inc. - $SDGR

Schrödinger has developed a physics-based computational platform that enables discovery of high-quality molecules for drug development and materials applications faster than traditional methods, at a lower cost, and with a higher likelihood of success.

Sema4 - $CMLF

Sema4 is a patient-centered health intelligence company dedicated to advancing healthcare through data-driven insights. They have developed their own advanced analytics platform Centrellis™.

This enables Sema4 to build predictive models of human health to deliver personalized insights for patients in the areas of women’s health and precision oncology, as well as more generalized genomic health screening and modeling across the spectrum of disease.

The future of healthcare promises a more targeted, personalized treatment, cures for illnesses, and hope for better, more accessible care worldwide. I believe these companies among many others are pushing the industry forward and helping create the future of medicine.

Special thanks to @qcapital2020 for highlighting $SDGR in his excellent thread.

Also a big thank you to @anthonyohayon and @avinmash for showcasing the opportunity to get into $CMLF before it even was Sema4.

Which other companies are also worth researching in this space?