🚨Linoleic acid THREAD🚨

- the 45% fat from soybean oil, 55% milk protein diet (HFHP-soy) was 25%⬆️"energy dense" than the other 2

- HFHP-soy had the lowest adiposity index: 33%⬇️than the low-fat high-protein diet & 45%⬇️than the low-fat moderate-protein diet https://twitter.com/tednaiman/status/1357401781370638341
1/
HFHP-soy had the
- heaviest livers (i'm betting they were fatter)
- least WAT (despite having the most energy dense diet)
- least brown adipose tissue (that "burns fat")
- weighed the least compared to LFHP & LF-mod-protein
2/
HFHP-soy had the
- smallest subcu adipocyte diameters
- highest number of subcu adipocytes (cells/mg)

1) HFP-soy group has shifted their adipose tissue profile unfavourably, *despite* a lower total fat mass

2) the most energy dense diet gave the lowest adiposity index
3/
as expected
- energy density doesn't matter to obesity
- soybean oil interferes with adipocyte function
- protein positively affects total fat mass
- carbs aren't essential
4/
@tednaiman says they were "insulin sensitive" but no clamp, fasting insulin or anything was done to assess that - just fat cell measures. if anything, their fat cells got⬆️insulin sensitive! no bueno

& they were "healthy"? by what measure? certainly not their fat profile...
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