23andMe to go public via a merger.

Reportedly valued at $3.5 billion

Ticker symbol: $ME https://twitter.com/joelwinston/status/1357356823980957703

investment thesis slide.

do they even know how dystopian this sounds?

Useful ranking of largest gene databases. (*not verified by me, plus some databases more useful than others).

positioning DNA as consumer experience, alongside Airbnb

23andMe claims they have genotyped about 10 million people.

believe they have a virtuous cycle. Test consumers (genotype), get them to answer questions (phenotype), then give them more 'insights' products

quality of 23andMe phenotypes (surveys) is questionable but made up for in the big numbers

You can find this investor deck and other information about the merger, and 23andMe at this link: https://sec.report/Document/0000950103-21-001779/#dp145636_ex9902.htm that is where i am getting this from

Here is the 23andME ancestry product. I have added some details to the family tree for the lulz

On 23andMe's largest databases slide, they left out http://Ancestry.com , which is the largest. Twice as big as 23andMe. Might relate to whether the ancestry members can be recontacted for additional health info.

cartoon medicine

lays out a vision of how genome association studies can improve drug development that was in vogue circa 2004

measuring success as "new programs" and increasing number of hits in GWAS on common conditions.

Whereas in 2021 actual biotech success usually looks like engineering against super clear deterministic type genes---CF, SARS-Cov-2, rare disease, etc.

The 23andMe financials. They dont make it easy to read. Looks like a $66 million loss in 2020 on revenues of $305 million. Consumer revenues predicted to contract substantially over the next couple of years, fewer tests sold

Maybe never has been profitable? Founded in 2006.

More financials. Maybe the previous one was only the consumer side? Here it shows larger loss of $147 million on $305 million in revenue for 2020.

I am no CPA.

Deal details. Enterprise value of $3.5 billion. Will be interesting to see what the stock market says when $ME starts trading

tweeter asks about 23andMe drug pipeline.
https://twitter.com/ArtirKel/status/1357376177871024128

23andMe has got a immuno-oncology drug in phase 1, per their slides

Maybe same as this GSK/23andME phase 1

https://clinicaltrials.gov/ct2/show/NCT04446351?term=23andme&draw=2&rank=6

was this identified via GWAS lead?

ha. finally followed by Anne Wojcicki.

Only 15 years after co-writing the article that is said (by some) to have inspired the company. https://www.wsj.com/articles/SB116485210886636490

Long interview with Richard Branson and Anne Wojcicki

Good questions. As: Mostly platitudes

Concerned that Sir Branson takes too much sun