#WCLC20 Passionate plea to clinical investigators designing clinical trials by @jillfeldman4 at the @IASLC plenary. Eloquent articulation at some of the fundamental flaws in our research infrastructure. This is a must watch for trainees and experienced researchers alike. #LCSM
#WCLC20 We've seen drug approvals for lung cancer explode. But inclusion criteria have become more complex which has led to increasingly homogeneous trial participants. This is not progress; it limits generalization of trial results. Broaden criteria and boost accrual! #LCSM
#WCLC20 But expanding criteria only helps a fraction of our patients. The greatest barrier remains health disparities. We have to systematically address age-ism (median age in trials well below median age of disease) and income disparities as barriers to trial involvement.
#WCLC20 The racial disparities in trial participants starts a cycle - less participation means the results reflect an increasingly homogeneous population. As our treatments become more selective and sophisticated, this will limit the applicability of the findings even more. #LCSM
#WCLC20 To minimize disparities, we need to become familiar with the differences between equality, equity, and justice. We should aim for justice. #LCSM
#WCLC20 Recent legislature to ensure coverage for trial participation will help. As will training and education. As @jillfeldman4 puts it, the @IASLC #STARS Patient Research Advocate (PRA) program helps inform us on the "science and realities of lung cancer research" #LCSM
#WCLC20 Involvement. Engagement. @jillfeldman4 reminds us to ask questions and an important one is "Who is not at the table." This was a powerful and motivating talk - please log in to the @IASLC library to watch for yourself. #LCSM
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