Thanks to original sin, man is deprived of sanctifying grace and wounded in his nature. There are four wounds of the soul with which we must struggle as a result of original sin, each opposed to one of the four cardinal virtues (thread):
The first wound is Ignorantia, which darkens the intellect and makes it difficult to know the truth. It is opposed to the virtue of Prudence, and can be combated by contemplation, meditating on Revelation, and thoughtful discernment in obedience to the Divine Wisdom
The second wound is Malitia, which is a weakening of the power of the will. It is opposed to Justice (which fulfills duties and renders to each their due), and can be combated by discipline, especially fervent prayer and fasting
The third wound is Infirmitas, which causes us to recoil before difficulties in the struggle for the good, to trade good for evil out of fear of suffering. It is opposed to Fortitude, and combated by penance, mortification, and remembering one's sins
The fourth wound is Concupiscentia, which is the desire for the satisfaction of the senses against the judgement of reason. It is opposed to Temperance, and can be combated by meditation on one's death and judgement