There's a Malayalam movie in which the protagonist vows to kill Vasco da Gama after he burns a ship full of pilgrims on their way to Mecca.

Vasco da Gama did, in fact, burn a ship full of Muslim pilgrims. The Portuguese gained a notorious reputation in the 16th century for attacking Muslim shipping in the Indian Ocean. Near Calicut, in 1502, Gama captured large royal ship named "Meri" owned by the Mamluks.

“[B]ecause it was so large and secure, many honoured Muslims travelled on it on pilgrimage to their abomination of Mecca, and it returned with these pilgrims and also a very rich cargo.”
- João de Barros (d. 1570)

Gama burned the ship, rejecting the offer of the passengers to pay him off. One captain and some twenty children were spared, the former because his seafaring expertise and the latter in order to convert them to Christianity.

Source (open access): https://brill.com/view/title/33567