Stanford study reveals immune driver of brain aging
Blocking PGE2 reverses mental decline, restores brain metabolism.
But where does PGE2 come from? https://www.eurekalert.org/pub_releases/2021-01/sm-ssr011921.php
Blocking PGE2 reverses mental decline, restores brain metabolism.
But where does PGE2 come from? https://www.eurekalert.org/pub_releases/2021-01/sm-ssr011921.php
PGE2 is made from arachidonic acid, in turn made from membrane phospholipids.
The composition of membrane phospholipids depends on the ratio of omega-6 to omega-3 fatty acids in the diet.
The composition of membrane phospholipids depends on the ratio of omega-6 to omega-3 fatty acids in the diet.
The more omega-6 that people consume, the greater the amount of arachidonic acid in cell membranes.
More omega-3 (from fish or fish oil), the more DHA in membranes and less AA.
https://www.sciencedirect.com/science/article/pii/S0952327815000873
More omega-3 (from fish or fish oil), the more DHA in membranes and less AA.
https://www.sciencedirect.com/science/article/pii/S0952327815000873
Most of the omega-6 comes from linoleic acid, the primary component of, you guessed it, seed oils.
All of the above points to seed oils as a driver of brain aging.
So, don't consume them.
Unfortunately, they're everywhere in the food supply.
All of the above points to seed oils as a driver of brain aging.
So, don't consume them.
Unfortunately, they're everywhere in the food supply.
Over the past century, seed oil consumption rose, and over the past few decades, soybean oil consumption skyrocketed.