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What is > accurate to predict that a cystic pancreatic lesion is mucinous or not, intra-cystic CEA or glucose?
Look at this meta-analysis from Sandra Faias et al @GIE_Journal-follow the twitter thread
@ChahalPrabhleen @japariciot2 @Belenmm271 @lelecapurso @guspereztweets
Look at this meta-analysis from Sandra Faias et al @GIE_Journal-follow the twitter thread
@ChahalPrabhleen @japariciot2 @Belenmm271 @lelecapurso @guspereztweets
Meta-analysis based on surgical specimens (gold standard)
CEA: 31 studies, 2083 surgical patients
Glucose: 5 studies, 275 surgical patients
CEA: 31 studies, 2083 surgical patients
Glucose: 5 studies, 275 surgical patients
Glucose performed better than CEA for mucinous cysts diagnosis (premalignant and malignant)
Sensit. Specif. ROC AUC
Gluc 0.91 0.67 0.95
CEA 0.75 0.80 0.79
Sensit. Specif. ROC AUC
Gluc 0.91 0.67 0.95
CEA 0.75 0.80 0.79
"Glucose had a higher sensitivity (91%), with uncommon false negative results, making it an excellent biomarker to exclude a mucinous cyst. Sensitivity analysis demonstrated that the findings of the current meta-analysis are robust."
Have a look to the original @GIE_Journal paper! https://www.giejournal.org/article/S0016-5107(21)00048-1/fulltext?dgcid=raven_jbs_aip_email#%20
