Read on Twitter
"How Hard It is Seeing What Is In Front Of Your Eyes" is probably one of the most sentimental and insightful scientific articles of advice I ever read 
https://www.cell.com/cell/fulltext/S0092-8674(18)30795-5#.YAzEbAVy3R4.twitter
#Immunology #ScienceTwitter #Science #History #Amazing
https://www.cell.com/cell/fulltext/S0092-8674(18)30795-5#.YAzEbAVy3R4.twitter #Immunology #ScienceTwitter #Science #History #Amazing
2/Spoiler: the story is about how the Nobel Prize-worthy discovery by Chris Anfinsen of how amino acid sequence determines protein structure in 1950s/60s was also independently made by PhD student Lisa Steiner..
3/who is btw the first woman faculty member of @MITBiology
https://biology.mit.edu/profile/lisa-steiner/
#WomenInSTEM
https://biology.mit.edu/profile/lisa-steiner/
#WomenInSTEM
4/What is astounding was that both her PhD advisor and committee thought the findings were not worth publishing and the results remained hidden in her thesis
5/Another CRUCIAL side-note: Dr. Steiner later postdoc-ed with M. Sela and H. Eisen was likely hugely influential in answering a question that haunted immunology: Does the specificity of antibody molecules reside in their amino acid sequence? YES, essentially the same rules that
6/she confirmed earlier with proteins (antibodies are proteins btw so unsurprising but REALLY important)
One question remains: Why did they not publish the results of her PhD?
One question remains: Why did they not publish the results of her PhD?
7/John Edsall, another big scientist in protein biology attempted an answer:
8/This is a VERY important lesson for our time, since we are now prone to getting so much data from high throughput #technologies including scRNA-seq, proteomics, metabolomics that we cannot explain because the field has not matured yet to understand their significance.
