"Aerosols..within the most breathable size range between 0.5 & 5 μm, can carry SARS-CoV-2 deep to the terminal alveoli..if this transmission pathway does exist, it would bypass the mucociliary clearance & incubation period of the virus in the upper airways
https://pubs.acs.org/doi/10.1021/acsnano.0c08484?s=09
The filtration material itself of N95's average pore size ~0.3−0.5 μm does not block finer aerosol laden with virions penetration, not to mention surgical masks. For example, see Balazy et al. (2006).
Indoor airborne virus concentrations have been shown to exist (in day-care facilities, health centers, and on-board airplanes) primarily as aerosol particles of diameters smaller than 2.5 μm, such as in the work of Yang et al. (2011)
On average, 64% of the viral genome copies were associated with fine particles smaller than 2.5 μm, which can remain suspended in the air for hours.
"Such small particles (< 2.5 μm) are part of air fluidity, are not subject to gravitational sedimentation, and would not be stopped by long-range inertial impact. The slightest facial misfit of a mask renders the design filtration norm of the mask entirely irrelevant."
"MID (minimal infective dose) is amply surpassed by the virions carried in a single aerosol particle able to evade mask-capture:
There are typically 10 to 3rd power − 10 to 7th power virions per aerolized influenza droplet with diameter 1 μm − 10 μm
MID is 1 aerolized droplet"
"Therefore, the studies that show partial stopping power of masks, or that show that masks can capture many large droplets produced by a sneezing or coughing mask-wearer, in light of the above-described features of the problem, are irrelevant."
How breathing through masks increases the nebulization effect: breathing through mask material splits larger aerosols into smaller ones which reach deeper all the way to the lung's alveoli bypassing mucosal immunity. Thread starts here ⬇️
https://twitter.com/robinmonotti/status/1349997185006497793?s=19
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