The number of publications about the impact of #vitaminD on the #COVID19 pandemic is exploding. In the first 2 weeks of January alone, @Scopus recorded 29 new scientific papers addressing this topic. I'll provide you with an overview of the most cited papers. #UnbiasedScience

(1) Rhodes et al. (2021) observed a correlation between latitude and #COVID mortality rate. They state that "this supports a role for ultraviolet B acting via vitamin D synthesis". They strongly advise vitamin D deficient people to take supplements. https://onlinelibrary.wiley.com/doi/10.1111/joim.13149

(2) Munshi et al. (2021) report that patients with a poor prognosis had a significantly lower vitamin D level and conclude that "diagnosis of vitamin D deficiency could be a helpful adjunct in assessing patients' potential of developing severe COVID-19." https://onlinelibrary.wiley.com/doi/10.1002/jmv.26360

(3) Shakoor et al. (2021) discuss "the role of these dietary components in immunity as well as their specific effect in COVID-19 patients" in their review paper, and how supplementation of these nutrients may be used to decrease the mortality rates. https://www.maturitas.org/article/S0378-5122(20)30346-7/fulltext

(4) Wang et al. (2021) from Havard University present a trial design that will be able to assess the effect of Vitamin D supplementation for early treatment and post-exposure prophylaxis of COVID-19. https://www.sciencedirect.com/science/article/pii/S1551714420302548?via%3Dihub

(5) Tang et al. (2021) observed the impact of the sun on the test positive rate. However, this significant negative correlation only applied in census regions 1 & 2 of the U.S. (i.e. North & North-East. See the following graphic: https://ars.els-cdn.com/content/image/1-s2.0-S0048969720353456-gr1.jpg) https://www.sciencedirect.com/science/article/pii/S0048969720353456?via%3Dihub

(6) Cereda et al. wrote a review on the benefit and mechanism of Vit-D and state that "cautious interpretation of the significance of low vitamin D25OH levels is advisable" in particular with respect to infection prevention & clinical outcome improvements. https://journals.lww.com/co-clinicalnutrition/Abstract/2021/01000/A_brief_discussion_of_the_benefit_and_mechanism_of.17.aspx

(7) Fedele et al. (2021) state that "vitamin D deficiency has been reasonably correlated to COVID-19 as a pathogenic factor" and that "a prevalence of vitamin D deficiency is 35% higher in obese individuals regardless of latitude and age." https://linkinghub.elsevier.com/retrieve/pii/S0899900720302999

The evidence base on the positive impact of #vitaminD on #COVID19 is relatively good. More and more publications will be published on this topic in the course of the months using clinical data from 2020. I will keep you posted throughout the year. Sunshine and stay "postivie"!

@threadreaderapp please unroll kthxbye