learning from our mistakes, and taking lessons from those who have handled this pandemic best

a Trainspotting inspired🧵1/n https://twitter.com/BBCScotNine/status/1347627955665711110
we now know that this was wrong 3/n
the deadliest infectious disease event of the last century, the 1918-19 Spanish Influenza pandemic, was propagated by the main form of mass transportation at the time: sea travel during the closing stages of World War I 4/n
this century’s deadliest pandemic (*so far*) has in turn been spread by international air travel

numerous research studies in the countries hardest hit by Covid-19 (United Kingdom, United States, Brazil) have arrived at the same findings regarding importation 5/n
the virus arrives in hundreds or thousands of separate events, and from these is seeded to spread throughout the entire population

https://science.sciencemag.org/content/early/2021/01/07/science.abf2946 @ScienceMagazine @laduplessis @arambaut @erikmvolz 6/n
by the 14th of January we knew that there was human to human transmission
https://twitter.com/UNGeneva/status/1217146107957932032 9/n
but in Scotland we were too slow to act: advice was issued to self-isolate after returning from travel to selected parts of Northern Italy only, and not from Italy as a whole, 4 days later
https://www.gov.scot/news/coronavirus-travel-advice-updated/ 12/n
only on the 10th of March did the Scottish government advise all international travellers to self-isolate on return from travel abroad

and only in early June did the UK government start to enforce these quarantine rules 13/n
the first lockdown, although painful in a number of ways, and extended for longer in Scotland than in England, was highly effective

by some days in July we were down to just 2 confirmed Covid-19 cases in the *entire country* @TravellingTabby @P_H_S_Official 14/n
further research, conducted by my academic and NHS colleagues, suggests that there were only a handful of viral lineages left at this point in Scotland, each causing a small number of cases 15/n

https://www.cogconsortium.uk/wp-content/uploads/2020/12/9th-December-2020-COG-UK-Report-Scotland-SARS-CoV-2-a-genomics-perspective-SAGE.pdf
but by September we were back to rising case counts. The source of these new cases?

travel again, this time from England and continental Europe 16/n
screening travellers is not enough

we know that airport screening is resource intensive, and often ineffective due to the incubation time of the virus
https://www.cochrane.org/news/cochrane-rapid-review-investigates-effectiveness-screening-covid-19

RT-PCR without enforced quarantine is ineffective too 17/n
the countries that have handled this pandemic best are those that have been able to secure and control the passage of people across their borders 18/n
Taiwan, Australia and New Zealand, to pick from the small number of countries that have managed to keep case counts relatively low, introduced stringent travel restrictions from the start of the pandemic 19/n
most importantly, they adopted measures to ensure that new arrivals complied with quarantine regulations 20/n
in contrast in a Scotland with (at last count) 2309 cases a day, this degree of disease surveillance and control remains a distant dream

more vaccines will be arriving soon, but so far only just over 100,000 adults have been vaccinated

leaving 4.3 million unprotected 23/n
even these optimistic schedules are contingent on vaccine availability: manufacturers are already struggling to keep up with demand https://metro.co.uk/2021/01/01/covid-vaccine-supply-issues-could-delay-life-getting-back-to-normal-13833708/

in addition, we have no clinical trials to guide vaccinating the 1 million children and young people in Scotland 25/n
given that we can’t rely on vaccines to get us out of our current dire situation

let’s learn from our previous mistakes, and take lessons from those who have handled the pandemic best

Let's: 26/n
Choose to continue to restrict travel, including from England, unless it is absolutely essential
https://www.gov.scot/publications/coronavirus-covid-19-update-first-ministers-statement-monday-4-january-2021/ 27/n
Choose to strictly enforce breaches of travel quarantine 28/n
Choose to think hard about continuing these travel restrictions beyond lockdown, until national case numbers are so low that we can effectively investigate and contain local outbreaks 29/n
Choose to seamlessly transition from a Scotland with very low case numbers, to one where everyone is vaccinated 30/n
Choose to minimise unnecessary death and disruption to healthcare and education 31/n
Choose to make sure that this lockdown is the last one we have to endure 32/n
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