Read on Twitter
Interesting thread on a new genomic technology getting a lot of hype. But until they release more details on how their method actually works, this is an ad, not science https://twitter.com/bionanogenomics/status/1347213793827442690
This figure took me over 10 minutes to find on their website (buried at the very bottom of the Applications page) and is still frustratingly sparse
Saying you used your proprietary software does not qualify as a methods section guys
Full "preprint" here. Notice the schematic I posted above is not present (probably because they don't describe the technology whatsoever) https://www.biorxiv.org/content/10.1101/2020.07.15.205245v1
Unrelated hot take: Circos plots are almost always uninterpretable (also maybe label your colors)
Are karyotyping and CMAs outdated? Of course. But at least we know how they work, and can plan around their blind spots accordingly.
But I don't see how you can expect to put this in the clinic while it remains this much of a black box
But I don't see how you can expect to put this in the clinic while it remains this much of a black box
Not my expertise, but it seems like the IP on their actual optical mapping instrument should be enough to prevent copycats?
Release. The. Code. This is such a cool bioinformatics problem that lots of people would love to work on, essentially improving your software for free
Release. The. Code. This is such a cool bioinformatics problem that lots of people would love to work on, essentially improving your software for free
Curious to hear what others think (esp. @RyanLCollins13), let me know if I'm missing something big
