Here is my COVID math. I am 58 with hopefully, say, 20 good years.

Life given up from year in quarantine: 1 in 20
Chance of contracting & dying of COVID in one year at my age: 1 in 1500
Approx. chance of death from vaccine reaction: 1 in 50,000

By this math:
1. I have zero desire to give up 5% of my life to remove a 0.6% chance of dying.
2. I am happy to take a vaccine -- the odds are good compared to chance of death from COVID and it is really worth it to me if the government will leave me alone after I take it

My fear of course in #2 is that just as I am having a hard time breaking the twitter habit and walking away, government officials can't break the power habit either and won't walk away from their new found powers -- new excuses will be found to make me miserable.

But note that these are not hard choices for me. Each are separated by a full 1-2 orders of magnitude.

Folks have said that I am not really giving up a full year, there is still life under quarantine. Well, that depends on where you get your happiness and mental wellness.

But even at only 10% life impairment, I am losing 0.5% of my life vs. a risk that is 10x less.