1/ #MedTwitter! Good morning! We’re excited to bring you our latest installment of #ReadingRoom. Dim the lights, and let’s dive in!

Take a look at the scan below. What’s your diagnosis? Where do you think it might’ve come from?
2/ You’ve got multiple sites of bleeding in the brain. No signs of trauma. Doesn’t follow a vascular territory. The bleed spares the cortex, and each hemorrhage is surrounded by edema. This is the classic and unfortunate appearance of hemorrhagic brain mets.
3/ In describing the bleed in the previous tweet, we hinted at the differential for a brain bleed. The table below summarizes that differential and the distinguishing characteristics of each type of hemorrhage.
4/ Once you’ve identified hemorrhagic brain mets, the next task is to identify the source, if not already known.
6/ To recap: bleeding in the brain may come from trauma, hemorrhagic conversion of a stroke or hemorrhagic mets. Once those metastasis have been identified, the origin is likely to be found from a short list of the most common cancers that go to the brain and bleed.
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