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If biological sex were truly binary, hormonal transition wouldn’t work because my body would be “male” and would therefore be completely insensitive to higher-order estrogenic effects on the cellular level that result in feminization.
There are no “male” bodies or “female” bodies, there are just bodies with characteristics arising from genetic and hormonal influences. Humans are a mosaic, a bimodal distribution of outcomes resulting from the dance between genetics, hormones, and cumulative epigenetic feedback.
The reason hormonal transition works is precisely because bodies generally can respond to either sex hormone as dominant. Our cells contain receptors that are activated by either binding estrogen or testosterone, responding to produce what we call “secondary sex characteristics.”
Finally, the reason our bodies have such capabilities is because there are no “male” eggs or “female” eggs. We all become who we are physically through a syncopated dance of biomolecular synthesis orchestrated by endocrinological signaling from gestation through puberty.
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