Understanding why the mRNA in the Pfizer/Moderna vaccines cannot change your DNA, explained to diff audiences:
(1) Young kids: DNA and mRNA are kept in separate parts of the cell.
(2) High school: DNA is inside the nucleus, and mRNA cannot get access to it.
(1) Young kids: DNA and mRNA are kept in separate parts of the cell.
(2) High school: DNA is inside the nucleus, and mRNA cannot get access to it.
(3) Undergrads (non science): the flow of info in our cells goes from DNA to RNA to proteins.
This cannot be reversed in the absence of a special enzyme, which our cells don’t contain. Nor does the mRNA in the vaxcine have the tag needed to get the mRNA into the nucleus.
This cannot be reversed in the absence of a special enzyme, which our cells don’t contain. Nor does the mRNA in the vaxcine have the tag needed to get the mRNA into the nucleus.
(4) Bio Undergrad/Grad students: in order to enter the nucleus, a macromolecule as large as mRNA would need to be artificially tagged with a nuclear localization signal.
Without it, the mRNA could not associate with importin proteins to use small G-protein mediated transport across the nuclear pore complex. Additionally, coronaviruses do not possess Rev Transcriptase as they are positive strand RNA viruses.