If you want to have the biggest possible impact in tech, I think you should still move to the Bay Area.

The people here, and the network effects caused by that, are worth it.

It's hard to overstate the magic of lots of competent, optimistic people in one place.
The future will certainly be more distributed, but I think that a large fraction of the most important US companies started in the next decade will continue to be within 50 miles of SF.
It's easy to not be in the Bay Area right now, because there's not much to miss out on. As soon as stuff restarts, and the most interesting meetings, dinners, events, and parties are here, I predict FOMO brings a lot of people back fast :)
Zoom isn't the same. It's fine when everyone is using it for their meetings, but it will be different when only 50% of people are.
All of the problems are true--the city and state are horribly mismanaged (and so the quality of life, particularly relative to the costs, is bad), it's over-regulated, the monoculture is not good, etc etc.
Someday the Bay Area might be the wrong choice. The incompetence of state and local government could eventually become intolerable. Or VR could change everything.

But for now, I think fight instead of flight is the better choice. Let's help fix things.
I am super thankful for the opportunities I've had here. I'm excited to pay it forward.

(And I would love to see @LondonBreed using Twitter like @FrancisSuarez!)
This is the best time in a long time to move here, actually. The people coming are the ones who are earnestly motivated, and the costs are lower than they've been in a long time.
You can follow @sama.
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