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SARS-CoV-2 is getting all these strange mutations 
. Do I need to get worried, as the vaccine may not work??
The simple answer is: Mostly Likely NO
- SARS-CoV-2 is also an RNA virus and we know that all RNA viruses evolve rapidly during multiple cycles of replication.
. Do I need to get worried, as the vaccine may not work?? The simple answer is: Mostly Likely NO
- SARS-CoV-2 is also an RNA virus and we know that all RNA viruses evolve rapidly during multiple cycles of replication.
- During this process, some RNA viruses are able to accept mutations to their surface proteins in such a way that they may partially escape human immunity. This process is known as "antigenic drift". The beta-Coronavirus genus also has this "antigenic drift" capability.
- Though there are many we know about the following considerable antigenic variants of SARS-CoV-2: based on spike protein variation: N439K, N501Y, S477N. Y453F, D80Y, etc.
- Now, certain genetic variants may spread more than others based on natural selection and partial local immunity to previously infecting variants. So, continue to use #FaceMask and practice #Handhygiene 
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#IDTwitter
.#IDTwitter
- Most of these variants have only a single mutation and mostly don't affect the spike receptor-binding domain. Such single mutations will generally have little impact on the polyclonal strong immune response that we develop due to the mRNA vaccines. Hence, get your #bestshot.
