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A response to Dr. Chris Palmer: Is LDL an independent risk factor for heart disease? https://thedietwars.com/a-response-to-dr-chris-palmer-is-ldl-an-independent-risk-factor-for-heart-disease/?utm_source=ReviveOldPost&utm_medium=social&utm_campaign=ReviveOldPost
Dr. Palmer also included the following correction tweet: https://twitter.com/ChrisPalmerMD/status/1335620209860808710
These are fine. LDL definitely is an independent risk factor for CVD in people without pre-existing CVD; but some have argued that it just hasn't been shown convincingly that reducing via statin therapy reduces risk of CVD without pre-existing CVD. However...
The part below is just false. LDL lowering in folks with pre-existing CVD where all else is normal in fact does improve outcomes. https://twitter.com/ChrisPalmerMD/status/1335621052026806275
I discuss this at length in my post, but here is the link and passage that is relevant to this claim.
https://jaoa.org/article.aspx?articleid=2093916
https://jaoa.org/article.aspx?articleid=2093916
One wonders what @ChrisPalmerMD's motivation is here. If he wants to dispute whether primary prevention reduces risk, he is on solid enough ground and can make that case with plenty of evidence to call upon to support him... But
But saying that LDL is not an independent risk factor when metabolic syndrome is not present is false; and it is not true that LDL lowering in people without metabolic syndrome with pre-existing CVD will not see benefit.
They absolutely will, and suggesting that they might not is a disservice to patients and public health
Matthews et al. estimated the health effect of a short period of negative media coverage of statins: between 2000-6000 excess cardiovascular events
https://www.bmj.com/content/353/bmj.i3283
Matthews et al. estimated the health effect of a short period of negative media coverage of statins: between 2000-6000 excess cardiovascular events
https://www.bmj.com/content/353/bmj.i3283
The only legitimate controversy here is whether statin therapy improves outcomes in primary prevention (without pre-existing CVD). Everything about metabolic syndrome is speculative and not supported by any clinical trial evidence that I am aware of.
I would like to conclude by pointing out that this comment with respect to libel is unnecessary and inaccurate. Libel consists of statements that are defamatory and false. My statements are scientifically accurate and some of Dr. Palmer's are false. https://twitter.com/ChrisPalmerMD/status/1335620209860808710
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