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"Antiviral Activity of Ivermectin Against SARS-CoV-2: An Old-Fashioned Dog with a New Trick - A Literature Review"
https://www.researchgate.net/publication/343689933_Antiviral_Activity_of_Ivermectin_Against_SARS-CoV-2_An_Old-Fashioned_Dog_with_a_New_Trick_-_A_Literature_Review
https://www.researchgate.net/publication/343689933_Antiviral_Activity_of_Ivermectin_Against_SARS-CoV-2_An_Old-Fashioned_Dog_with_a_New_Trick_-_A_Literature_Review
"A key aspect of the infectious cycle of many viruses is the transport of specific viral proteins into the host cell nucleus to perturb the antiviral response. Examples include a number of RNA viruses [i.e. SARSCov2] that are significant human pathogens" https://www.researchgate.net/publication/228101908_Nuclear_trafficking_of_proteins_from_RNA_viruses_Potential_target_for_antivirals
"We have reviewed anti-SARS-CoV-2 potencies of available antiviral drug groups such as fusion inhibitors, protease inhibitors, neuraminidase inhibitors, and M2 ion-channel protein blockers."
https://www.researchgate.net/publication/342867143_Antivirals_for_COVID-19_A_critical_review
https://www.researchgate.net/publication/342867143_Antivirals_for_COVID-19_A_critical_review
IVERMECTIN "A single dose of the drug induced ~5000-fold reduction in viral RNA content" [in vitro]. https://www.sciencedirect.com/science/article/pii/S2213398420301767
"The broad-spectrum antiviral activity of ivermectin against several RNA viruses is mediated by the inhibition of importin α/β1-mediated nuclear import."
"SARS-CoV-2 being an RNA virus, a similar mechanism is expected to facilitate the inhibitory activity of ivermectin."
"Ivermectin has recently exhibited potent in vitro antiviral activity against SARS-CoV-2. A single dose of the drug induced ~5000-fold reduction in viral RNA content" https://www.sciencedirect.com/science/article/pii/S2213398420301767#bib143
IVERMECTIN: "Impedes the host import in alpha/beta-1 nuclear transport proteins, which are a central part of the intracellular transport process that viruses seize to increase infection by pacifying the host’s antiviral response." https://archive.vn/v0nKK
