Just read the pre-print paper. This is looking very good indeed, best of all vaccine candidates so far. Short thread follows. https://twitter.com/ETHealthWorld/status/1339412593123856384
Covaxin is a killed vaccine. Two doses 14 days apart protocol, followed up for six months.
Covaxin is a killed vaccine. Two doses 14 days apart protocol, followed up for six months.
Covaxin is a killed vaccine. Two doses 14 days apart protocol, followed up for six months.
Number of candidates 375. Out of the initially screened 522 candidates, 133 tested positive even before the trial started.
Only one “serious” adverse effect noted, one patient developed mild COVID five days after first vaccination dose. As this is a killed vaccine, it’s definitely not due to the vaccine. Patient recovered uneventfully. No other major adverse effects.
Seroconversion 87-92% and similar with lower and higher doses. Compared to 8% seroconversion in control group (community spread). So highly effective and safe. Ticks all the boxes. Now onwards to phase 3 trials.
Covaxin trial preprint link.
https://www.medrxiv.org/content/10.1101/2020.12.11.20210419v1.full.pdf
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